J
Jean-Jacques Grob
Researcher at Aix-Marseille University
Publications - 369
Citations - 58038
Jean-Jacques Grob is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Medicine & Melanoma. The author has an hindex of 71, co-authored 310 publications receiving 45788 citations. Previous affiliations of Jean-Jacques Grob include University of Sydney.
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Journal ArticleDOI
Role of tumor necrosis factor-α in Sneddon-Wilkinson subcorneal pustular dermatosis : a model of neutrophil priming in vivo
Jean-Jacques Grob,J. L. Mege,Christian Capo,E. Jancovicci,J.R. Fournerie,Pierre Bongrand,Jean-Jacques Bonerandi +6 more
TL;DR: A patient with IgG-kappa-associated subcorneal pustular dermatosis refractory to dapsone, etretinate, and plasma exchange was successfully treated with corticosteroids, and results suggest that a hyperactivation of neutrophils in the skin is due at least partly to excessive production of tumor necrosis factor-alpha.
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Long-term outcomes in patients (pts) with ipilimumab (ipi)-naive advanced melanoma in the phase 3 KEYNOTE-006 study who completed pembrolizumab (pembro) treatment.
Caroline Robert,Georgina V. Long,Jacob Schachter,Ana Arance,Jean-Jacques Grob,Laurent Mortier,Adil Daud,Matteo S. Carlino,Catriona M. McNeil,Michal Lotem,James Larkin,Paul Lorigan,Bart Neyns,Christian U. Blank,Teresa M. Petrella,Omid Hamid,Honghong Zhou,Blanca Hornet Moreno,Nageatte Ibrahim,Antoni Ribas +19 more
TL;DR: Long-term outcomes for all pts and in those pts who completed pembro therapy are presented, with superior PFS and OS vs ipi in ipi-naive pts with advanced melanoma in the phase 3 KEYNOTE-006 study.
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TREATMENT OF LARGE BASAL-CELL CARCINOMAS WITH INTRALESIONAL INTERFERON-ALPHA-2a
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Large keratoacanthomas treated with intralesional interferon alfa-2a.
Jean-Jacques Grob,F. Suzini,Marie Aleth Richard,M. Weiller,H. Zarour,C. Noe,M.H. Munoz,Jean-Jacques Bonerandi +7 more
TL;DR: The results suggest that this treatment hastens healing and limits scarring in giant keratoacanthomas.
Journal ArticleDOI
Ugly Duckling Sign as a Major Factor of Efficiency in Melanoma Detection
Caroline Gaudy-Marqueste,Yanal Wazaefi,Y. Bruneu,Raoul Triller,Luc Thomas,Giovanni Pellacani,Josep Malvehy,M.-F. Avril,Sandrine Monestier,Marie-Aleth Richard,Bernard Fertil,Jean-Jacques Grob +11 more
TL;DR: Intrapatient comparative analysis is of major importance to the effectiveness of the diagnosis of melanoma and introducing IPCA using the ugly duckling sign in computer-assisted diagnosis systems would be expected to improve performance.