J
Jean-Jacques Grob
Researcher at Aix-Marseille University
Publications - 369
Citations - 58038
Jean-Jacques Grob is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Medicine & Melanoma. The author has an hindex of 71, co-authored 310 publications receiving 45788 citations. Previous affiliations of Jean-Jacques Grob include University of Sydney.
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Journal ArticleDOI
Pimasertib Versus Dacarbazine in Patients With Unresectable NRAS-Mutated Cutaneous Melanoma: Phase II, Randomized, Controlled Trial with Crossover
Céleste Lebbé,Caroline Dutriaux,Thierry Lesimple,Willem Kruit,Joseph Kerger,Luc Thomas,Bernard Guillot,Filippo de Braud,Claus Garbe,Jean-Jacques Grob,Carmen Loquai,Virginia Ferraresi,Caroline Robert,Paul Vasey,Robert M. Conry,Richard Isaacs,Enrique Espinosa,Armin Schueler,Giorgio Massimini,Brigitte Dreno +19 more
TL;DR: Pimasertib has activity in NRAS-mutated cutaneous melanoma and a safety profile consistent with known toxicities of MEK inhibitors and overall survival (OS), objective response rate (ORR), quality of life (QoL), and safety.
Journal ArticleDOI
Human Polyomavirus-6 Infecting Lymph Nodes of a Patient With an Angiolymphoid Hyperplasia With Eosinophilia or Kimura Disease
Nicolás Rascovan,Sonia Bouchard,Jean-Jacques Grob,Anne-Marie Collet-Villette,Caroline Gaudy-Marqueste,M. Penicaud,Hubert Lepidi,Didier Raoult,Christelle Desnues +8 more
TL;DR: This work provides direct evidence of HPyV6 infecting a lymph node of a patient with an angiolymphoid hyperplasia with eosinophilia or Kimura disease.
Journal ArticleDOI
Adjuvant interferon alfa in malignant melanoma: an interdisciplinary and multinational expert review.
Paolo A. Ascierto,Helen Gogas,Jean-Jacques Grob,Salvador Martin Algarra,Peter Mohr,Johan Hansson,Axel Hauschild +6 more
TL;DR: The data suggest greater responses in patients with stage III micro- Metastatic versus macro-metastatic disease, and ulceration may also predict greater sensitivity to therapy, although further investigation is needed.
Journal ArticleDOI
Why are quality of life instruments not recognized as reference measures in therapeutic trials of chronic skin disorders
TL;DR: Patient-reported outcomes, especially heath-related quality of life (HRQOL) outcomes, are particularly relevant for chronic skin disorders (CSDs), because lesion scores such as PASI are less meaningful in making therapeutic decisions.
Journal Article
The relation between seborrheic keratoses and malignant solid tumours. A case-control study.
Jean-Jacques Grob,M. C. Rava,J. Gouvernet,P. Fuentes,L. Piana,M. Gamerre,J. C. Sarles,J. J. Bonerandi +7 more
TL;DR: It was showed that solid malignancies are not generally associated with an increase in the number or size of seborrheic keratosis lesions, thus suggesting that they are not controlled by a hypothetical secretion of growth factors by tumours.