J
Jean-Jacques Mourad
Researcher at French Institute of Health and Medical Research
Publications - 111
Citations - 2777
Jean-Jacques Mourad is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Blood pressure & Perindopril. The author has an hindex of 26, co-authored 111 publications receiving 2562 citations.
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Journal ArticleDOI
Angiotensin-converting enzyme inhibitors reduce mortality in hypertension: a meta-analysis of randomized clinical trials of renin–angiotensin–aldosterone system inhibitors involving 158 998 patients
Laura C van Vark,Michel E. Bertrand,K. Martijn Akkerhuis,Jasper J. Brugts,Kim Fox,Jean-Jacques Mourad,Eric Boersma +6 more
TL;DR: In patients with hypertension, treatment with an ACE inhibitor results in a significant further reduction in all-cause mortality, and the widespread use of ACE inhibitors may result in an important gain in lives saved.
Journal ArticleDOI
The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway.
Anne-Paule Gimenez-Roqueplo,Judith Favier,Pierre Rustin,Jean-Jacques Mourad,Pierre-François Plouin,Pierre Corvol,Agnès Rötig,Xavier Jeunemaitre +7 more
TL;DR: Inactivation of the SDHD gene in hereditary paraganglioma is associated with a complete loss of mitochondrial complex II activity and with a high expression of angiogenic factors.
Journal Article
[Assessment of antihypertensive compliance using a self-administered questionnaire: development and use in a hypertension clinic].
TL;DR: La mise au point d'un questionnaire qui evalue l'observance des traitements antihypertenseurs pourrait etre un moyen de depistage, en pratique clinique quotidienne, des hypertendus ayant une mauvaise observance.
Journal Article
Aortic pulse wave velocity, an independent marker of cardiovascular risk.
TL;DR: Aortic pulse wave velocity (PWV), a classical index of aortic stiffness, may be easily measured in humans using non-invasive ultrasound methods of high reproducibility as discussed by the authors.
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Validation of two devices for self-measurement of blood pressure by elderly patients according to the revised British Hypertension Society protocol: the Omron HEM-722C and HEM-735C.
Luiz Aparecido Bortolotto,O. Henry,Olivier Hanon,Patrick Sikias,Jean-Jacques Mourad,Xavier Girerd +5 more
TL;DR: For elderly subjects both self-measurement devices satisfied the validation criteria of the BHS and therefore can be recommended for the clinical measurement of blood pressure in elderly patients.