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Jean-Richard Neeser

Researcher at Nestlé

Publications -  97
Citations -  5085

Jean-Richard Neeser is an academic researcher from Nestlé. The author has contributed to research in topics: Pathogenic bacteria & Dental plaque. The author has an hindex of 31, co-authored 97 publications receiving 4946 citations. Previous affiliations of Jean-Richard Neeser include University of Paris.

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Lactobacillus acidophilus LA 1 binds to cultured human intestinal cell lines and inhibits cell attachment and cell invasion by enterovirulent bacteria.

TL;DR: Investigation of the inhibitory effect of LA 1 organisms against Caco-2 cell adhesion and cell invasion by a large variety of diarrhoeagenic bacteria found incubation before and together with enterovirulent E coli were more effective than incubation after infection by E coli.
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Bifidobacterium strains from resident infant human gastrointestinal microflora exert antimicrobial activity

TL;DR: Several bifidobacterium strains from resident infant human gastrointestinalmicroflora exert antimicrobial activity, suggesting that they could participate in the “barrier effect” produced by the indigenous microflora.
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Adhesion of human bifidobacterial strains to cultured human intestinal epithelial cells and inhibition of enteropathogen-cell interactions

TL;DR: In this paper, 13 human bifidobacterial strains were tested for their ability to adhere to human enterocyte-like Caco-2 cells in culture, and the adhesion occurs to the apical brush border of the enterocytic Caco2 cells and to the mucus secreted by the human mucus-secreting HT29-MTX cell line.
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Identification and characterization of the eps (Exopolysaccharide) gene cluster from Streptococcus thermophilus Sfi6.

TL;DR: EPS expression in the non-EPS-producing heterologous host, Lactococcus lactis MG1363, showed that within the 15.25-kb region, a region with a size of 14.52 kb encoding the 13 genes epsA to epsM was capable of directing EPS synthesis and secretion in this host.
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The human Lactobacillus acidophilus strain LA1 secretes a nonbacteriocin antibacterial substance(s) active in vitro and in vivo

TL;DR: The spent culture supernatant of strain LA1 (LA1-SCS) contained antibacterial components active against S. typhimurium infecting the cultured human intestinal Caco-2 cells, and the LA1- SCS antibacterial activity was insensitive to proteases and independent of lactic acid production.