J
Jeannette Nardelli
Researcher at University of Paris
Publications - 20
Citations - 1223
Jeannette Nardelli is an academic researcher from University of Paris. The author has contributed to research in topics: Neurogenesis & Neural stem cell. The author has an hindex of 13, co-authored 20 publications receiving 1019 citations. Previous affiliations of Jeannette Nardelli include French Institute of Health and Medical Research & École Normale Supérieure.
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Journal ArticleDOI
Base sequence discrimination by zinc-finger DNA-binding domains
TL;DR: The results show that each finger spans three nucleotides and indicate two positions in Krox-20 zinc fingers that are important for base-pair selectivity, and modelling with molecular graphics suggests that these residues could bind directly with the bases and that other amino acid–base contacts are also possible.
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Zinc finger-DNA recognition: analysis of base specificity by site-directed mutagenesis.
TL;DR: A data base-guided site-directed mutagenesis analysis of Krox-20 provides new insights into the details of zinc finger-DNA interactions and illustrates both the potential and the difficulties of utilising these motifs for designing DNA-binding proteins with novel specificities.
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Cellular and molecular introduction to brain development
TL;DR: An overview of the cellular, molecular and genetic bases of brain development with an emphasis on the major mechanisms associated with landmarks of normal neural development in the embryonic stage and early postnatal life is provided.
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Cytomegalovirus-induced brain malformations in fetuses.
Natacha Teissier,Natacha Teissier,Catherine Fallet-Bianco,Anne-Lise Delezoide,Annie Laquerrière,Pascale Marcorelles,Suonavy Khung-Savatovsky,Suonavy Khung-Savatovsky,Jeannette Nardelli,Jeannette Nardelli,Sara Cipriani,Sara Cipriani,Zsolt Csaba,Olivier Picone,Jeffrey A. Golden,Thierry Van Den Abbeele,Thierry Van Den Abbeele,Pierre Gressens,Pierre Gressens,Pierre Gressens,Homa Adle-Biassette,Homa Adle-Biassette +21 more
TL;DR: The results indicate that the large spectrum of CMV-induced brain abnormalities is caused not only by tissue destruction but also by the particular vulnerability of stem cells during early brain development, and 2 main factors influence the neuropathologic outcome at this stage.
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Hippocampal Radial Glial Subtypes and Their Neurogenic Potential in Human Fetuses and Healthy and Alzheimer's Disease Adults.
Sara Cipriani,Isidre Ferrer,Eleonora Aronica,Gabor G. Kovacs,Catherine Verney,Jeannette Nardelli,Suonavy Khung,Anne-Lise Delezoide,Ivan Milenkovic,Sowmyalakshmi Rasika,Philippe Manivet,Jean-Louis Benifla,Nicolas Deriot,Pierre Gressens,Pierre Gressens,Homa Adle-Biassette +15 more
TL;DR: Pools of morphologically, antigenically, and topographically diverse neural progenitor cells are present in the human hippocampus from early developmental stages until adulthood, including in AD patients, while their neurogenic potential seems negligible in the adult.