J
Jee Hyun Kim
Researcher at Seoul National University Bundang Hospital
Publications - 703
Citations - 12600
Jee Hyun Kim is an academic researcher from Seoul National University Bundang Hospital. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 46, co-authored 319 publications receiving 9907 citations. Previous affiliations of Jee Hyun Kim include Seoul National University & New Generation University College.
Papers
More filters
Journal ArticleDOI
The growth inhibitory effect of lapatinib, a dual inhibitor of EGFR and HER2 tyrosine kinase, in gastric cancer cell lines.
Jin Won Kim,Hwang-Phill Kim,Seock-Ah Im,Soyeong Kang,Hyung Seok Hur,Young-Kwang Yoon,Do-Youn Oh,Jee Hyun Kim,Jee Hyun Kim,Dong Soon Lee,Tae-You Kim,Yung-Jue Bang +11 more
TL;DR: The results provide a rationale for the future clinical trials of lapatinib combined with cytotoxic drugs in the treatment of HER2-positive gastric cancer.
Journal ArticleDOI
HER2 Heterogeneity Affects Trastuzumab Responses and Survival in Patients With HER2-Positive Metastatic Breast Cancer
Hee Jin Lee,Hee Jin Lee,An Na Seo,Eun-Joo Kim,Min Hye Jang,Koung Jin Suh,Han Suk Ryu,Yu Jung Kim,Yu Jung Kim,Jee Hyun Kim,Jee Hyun Kim,Seock-Ah Im,Seock-Ah Im,Gyungyub Gong,Kyung Hae Jung,In Ae Park,In Ae Park,So Yeon Park,So Yeon Park +18 more
TL;DR: The results suggest that accurate assessment of HER2 status, including HER2 heterogeneity, is important in predicting trastuzumab responses and outcomes in patients with HER2-positive metastatic breast cancer.
Journal ArticleDOI
S-1 plus oxaliplatin versus capecitabine plus oxaliplatin for first-line treatment of patients with metastatic colorectal cancer: a randomised, non-inferiority phase 3 trial.
Yong Sang Hong,Young Suk Park,Ho Yeong Lim,Jeeyun Lee,Tae Won Kim,Kyu Pyo Kim,Sun Young Kim,Ji Yeon Baek,Jee Hyun Kim,Keun Wook Lee,Ik Joo Chung,Sang-Hee Cho,Kyung Hee Lee,Sang Joon Shin,Hye Jin Kang,Dong Bok Shin,Sook Jung Jo,Jae Won Lee +17 more
TL;DR: The SOX regimen could be an alternative first-line doublet chemotherapy strategy for patients with metastatic colorectal cancer and further investigation is needed to explore its potential when used together with other targeted agents or as adjuvant chemotherapy.
Journal ArticleDOI
Hepatitis B Virus Infection and B‐Cell Non‐Hodgkin's Lymphoma in a Hepatitis B Endemic Area: A Case‐control Study
Jee Hyun Kim,Yung-Jue Bang,Byung Joo Park,Taiwoo Yoo,Chul Woo Kim,Tae-You Kim,Dae Seog Heo,Hyo-Suk Lee,Noe Kyeong Kim +8 more
TL;DR: The present study suggests that the risk of B‐cell non‐Hodgkin's lymphoma is increased in HBV carriers and warrants further investigation of the possible role of hepatitis B virus in the pathogenesis of B-cell non-Hod gynaecological lymphoma.
Journal ArticleDOI
Histone deacetylase inhibitor enhances 5-fluorouracil cytotoxicity by down-regulating thymidylate synthase in human cancer cells.
Ju-Hee Lee,Jung Hyun Park,Yeonjoo Jung,Jee Hyun Kim,Hyun Soon Jong,Tae-You Kim,Yung-Jue Bang +6 more
TL;DR: It is reported that histone deacetylase inhibitors can reverse 5-FU resistance by down-regulating TS, and it is concluded that a combinatorial approach using histoneDeacetyl enzyme inhibitors may be useful at overcoming 5-fluorouracil resistance.