J
Jeff W.M. Bulte
Researcher at Johns Hopkins University School of Medicine
Publications - 356
Citations - 26823
Jeff W.M. Bulte is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Transplantation & Stem cell. The author has an hindex of 82, co-authored 342 publications receiving 24802 citations. Previous affiliations of Jeff W.M. Bulte include Johns Hopkins University & Pennsylvania State University.
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Journal ArticleDOI
Iron oxide MR contrast agents for molecular and cellular imaging.
TL;DR: SPIO‐based cellular imaging has now become an established technique to label and detect the cells of interest and is aimed at obtaining a deeper insight into the dynamics of in vivo cell biology, including lymphocyte trafficking, and at monitoring therapies that are based on the use of stem cells and progenitors.
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Magnetodendrimers allow endosomal magnetic labeling and in vivo tracking of stem cells
Jeff W.M. Bulte,Jeff W.M. Bulte,Trevor Douglas,Brian P. Witwer,Su-Chun Zhang,Erica Strable,Bobbi K. Lewis,Holly A. Zywicke,Brad Miller,Peter van Gelderen,Bruce M. Moskowitz,Ian D. Duncan,Joseph A. Frank +12 more
TL;DR: It is shown here that NSC-derived (and LacZ-transfected), magnetically labeled oligodendroglial progenitors can be readily detected in vivo at least as long as six weeks after transplantation, with an excellent correlation between the obtained MR contrast and staining for β-galactosidase expression.
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Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis.
Dimitrios Karussis,Clementine Karageorgiou,Adi Vaknin-Dembinsky,Basan Gowda-Kurkalli,John M. Gomori,Ibrahim Kassis,Jeff W.M. Bulte,Panayiota Petrou,Tamir Ben-Hur,Oded Abramsky,Shimon Slavin +10 more
TL;DR: Transplantation of MSCs in patients with MS and ALS is a clinically feasible and relatively safe procedure and induces immediate immunomodulatory effects.
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Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy
I. Jolanda M. de Vries,W. Joost Lesterhuis,Jelle O. Barentsz,Pauline Verdijk,J. Han van Krieken,Otto C. Boerman,Wim J.G. Oyen,Johannes J. Bonenkamp,Jan B.M. Boezeman,Gosse J. Adema,Jeff W.M. Bulte,Tom W. J. Scheenen,Cornelis J. A. Punt,Arend Heerschap,Carl G. Figdor +14 more
TL;DR: In vivo magnetic resonance tracking of magnetically labeled cells is feasible in humans for detecting very low numbers of dendritic cells in conjunction with detailed anatomical information and appears clinically safe and well suited to monitor cellular therapy in humans.
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In Vivo Magnetic Resonance Imaging of Mesenchymal Stem Cells in Myocardial Infarction
Dara L. Kraitchman,Alan W. Heldman,Ergin Atalar,Ergin Atalar,Luciano C. Amado,Bradley J. Martin,Mark F. Pittenger,Joshua M. Hare,Jeff W.M. Bulte +8 more
TL;DR: MRI tracking of MSCs is feasible and represents a preferred method for studying the engraftment of M SCs in MI.