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Jeff W.M. Bulte

Researcher at Johns Hopkins University School of Medicine

Publications -  356
Citations -  26823

Jeff W.M. Bulte is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Transplantation & Stem cell. The author has an hindex of 82, co-authored 342 publications receiving 24802 citations. Previous affiliations of Jeff W.M. Bulte include Johns Hopkins University & Pennsylvania State University.

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Dysprosium-DOTA-PAMAM dendrimers as macromolecular T2 contrast agents. Preparation and relaxometry.

TL;DR: The large temperature dependence suggests that the dominant mechanism of relaxation is the contact interaction effect, with the proton residence time as the primary time constant, and this largely unexplored relaxation mechanism has the potential to create a new class of T2-selective contrast agents.
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Conserved fate and function of ferumoxides‐labeled neural precursor cells in vitro and in vivo

TL;DR: It is shown that ferumoxides labeling does not affect NPC survival and pluripotency in vitro, and MRI cell tracking is well suited for non‐invasive monitoring of NPC transplantation.
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Synthesis of a probe for monitoring HSV1- tk reporter gene expression using chemical exchange saturation transfer MRI

TL;DR: The synthesis of the reporter probe, 5-methyl-5,6-dihydrothymidine (5-MDHT), which can be used for imaging of the herpes simplex virus type 1 thymidine kinase (HSV1-tk) reporter gene expression in rodents by MRI is described.
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Comparison of red-shifted firefly luciferase Ppy RE9 and conventional Luc2 as bioluminescence imaging reporter genes for in vivo imaging of stem cells

TL;DR: It is concluded that PRE9 has favorable properties as compared to luc2 in terms of pH independence, red-shifted spectrum, tissue light penetration, and signal quantification, justifying further optimization of protein expression and enzymatic activity.
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Structure-specific patterns of neural stem cell engraftment after transplantation in the adult mouse Brain

TL;DR: The ability of NSCs to migrate in the unlesioned adult mouse brain after stereotaxic transplantation into several structures including the cortex and hippocampus was tested, demonstrating variations in pattern of engraftment within different regions of the brain.