Preface to the Princeton Landmarks in Biology Edition vii Preface xi Symbols Used xiii 1. The Importance of Islands 3 2. Area and Number of Speicies 8 3. Further Explanations of the Area-Diversity Pattern 19 4. The Strategy of Colonization 68 5. Invasibility and the Variable Niche 94 6. Stepping Stones and Biotic Exchange 123 7. Evolutionary Changes Following Colonization 145 8. Prospect 181 Glossary 185 References 193 Index 201

The Theory of Island Biogeography

New evidence and consensus has led to further revision of the McDonald Criteria for diagnosis of multiple sclerosis. The use of imaging for demonstration of dissemination of central nervous system lesions in space and time has been simplified, and in some circumstances dissemination in space and time can be established by a single scan. These revisions simplify the Criteria, preserve their diagnostic sensitivity and specificity, address their applicability across populations, and may allow earlier diagnosis and more uniform and widespread use.

/pdf/diagnostic-criteria-for-multiple-sclerosis-2010-revisions-to-24iph50480.pdf

Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria

计量经济分析 = Econometric analysis

1. Introduction and Overview. 2. Detecting Influential Observations and Outliers. 3. Detecting and Assessing Collinearity. 4. Applications and Remedies. 5. Research Issues and Directions for Extensions. Bibliography. Author Index. Subject Index.

Regression Diagnostics: Identifying Influential Data and Sources of Collinearity

The 2010 McDonald criteria for the diagnosis of multiple sclerosis are widely used in research and clinical practice. Scientific advances in the past 7 years suggest that they might no longer provide the most up-to-date guidance for clinicians and researchers. The International Panel on Diagnosis of Multiple Sclerosis reviewed the 2010 McDonald criteria and recommended revisions. The 2017 McDonald criteria continue to apply primarily to patients experiencing a typical clinically isolated syndrome, define what is needed to fulfil dissemination in time and space of lesions in the CNS, and stress the need for no better explanation for the presentation. The following changes were made: in patients with a typical clinically isolated syndrome and clinical or MRI demonstration of dissemination in space, the presence of CSF-specific oligoclonal bands allows a diagnosis of multiple sclerosis; symptomatic lesions can be used to demonstrate dissemination in space or time in patients with supratentorial, infratentorial, or spinal cord syndrome; and cortical lesions can be used to demonstrate dissemination in space. Research to further refine the criteria should focus on optic nerve involvement, validation in diverse populations, and incorporation of advanced imaging, neurophysiological, and body fluid markers.

/pdf/diagnosis-of-multiple-sclerosis-2017-revisions-of-the-55ct02l5o1.pdf

Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria

The international competativeness of an industry is determined by its ability to sell goods and services of higher quality and/or at lower cost than its cometitors. Therefore, issues relating to international competitiveness can be conceptualised through their impact on sustained industry profitability. Using this framework, an index is then applied to the tourism industry using a case study where the industry's international competativeness is laregly dependent on natural environment related attributes and associated regulations. Complying with regulations can reduce competitiveness because of increases in the costs faced by the industry relative to competitors unaffected by regulations. However, it is also shown that compliance with regulations can also enhance the quality of natural environment related attributes-thus increasing industry revenue. Hence the impact of environmental regulations on international competitiveness depends on the outcome of these two opposing forces on industry profitability.

Environmental Regulations and the International Competitiveness of Australia's Tourism Industry- A Case Study of Far North Queensland

Inébilizumab réduit le risque de poussée dans la NMOSD indépendamment du polymorphisme du gène du récepteur III-A de la région Fc des IgG de faible affinité

Abstract 1264: High-resolution structures using cryo-EM guide drug development for Neuromyelitis Optica

This disclosure provides anti-HSPA5 antibodies. Also featured is a method for delivering an agent into the brain, spinal cord, or other component of the central nervous system. In addition, methods of identifying a human subject at risk of relapse of neuromyelitis optica (NMO) or neuropsychiatric systemic lupus erythematosus (NP-SLE) are disclosed, as are methods of determining the severity of an attack of NMO or NP-SLE, and methods of diagnosing NP-SLE.

Jeffrey Bennett

Papers

Environmental Regulations and the International Competitiveness of Australia's Tourism Industry- A Case Study of Far North Queensland

Inébilizumab réduit le risque de poussée dans la NMOSD indépendamment du polymorphisme du gène du récepteur III-A de la région Fc des IgG de faible affinité

Abstract 1264: High-resolution structures using cryo-EM guide drug development for Neuromyelitis Optica

Anti-hspa5 (grp78) antibodies and uses thereof

Sprinting to the Finish: Optical Coherence Tomography, Retinal Atrophy, and Neurodegeneration in Progressive Multiple Sclerosis.