J
Jeffrey M. Testani
Researcher at Yale University
Publications - 228
Citations - 9079
Jeffrey M. Testani is an academic researcher from Yale University. The author has contributed to research in topics: Heart failure & Renal function. The author has an hindex of 41, co-authored 196 publications receiving 5863 citations. Previous affiliations of Jeffrey M. Testani include Duke University & Cleveland Clinic.
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Journal ArticleDOI
Sotagliflozin in Patients with Diabetes and Recent Worsening Heart Failure
Deepak L. Bhatt,Michael Szarek,P. Gabriel Steg,Christopher P. Cannon,Lawrence A. Leiter,Darren K. McGuire,Julia B. Lewis,Matthew C. Riddle,Adriaan A. Voors,Marco Metra,Lars H. Lund,Michel Komajda,Jeffrey M. Testani,Christopher S. Wilcox,Piotr Ponikowski,Renato D. Lopes,Subodh Verma,Pablo Lapuerta,Bertram Pitt +18 more
TL;DR: In patients with diabetes and recent worsening heart failure, sotagliflozin therapy, initiated before or shortly after discharge, resulted in a significantly lower total number of deaths from cardiovascular causes and hospitalizations and urgent visits for heart failure than placebo.
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Potential Effects of Aggressive Decongestion During the Treatment of Decompensated Heart Failure on Renal Function and Survival
TL;DR: Hemoconcentration is significantly associated with measures of aggressive fluid removal and deterioration in renal function and is associated with substantially improved survival, raising the question of whether aggressive decongestion, even in the setting of worsening renal function, can positively affect survival.
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The use of diuretics in heart failure with congestion - a position statement from the Heart Failure Association of the European Society of Cardiology
Wilfried Mullens,Kevin Damman,Veli-Pekka Harjola,Alexandre Mebazaa,Hans-Peter Brunner-La Rocca,Pieter Martens,Jeffrey M. Testani,W.H. Wilson Tang,Francesco Orso,Patrick Rossignol,Marco Metra,Gerasimos Filippatos,Gerasimos Filippatos,Petar M. Seferovic,Frank Ruschitzka,Andrew J.S. Coats +15 more
TL;DR: The manuscript addresses frequently encountered challenges, such as evaluation of congestion and clinical euvolaemia, assessment of diuretic response/resistance in the treatment of acute heart failure, and an approach towards stepped pharmacologic diUREtic strategies, based upon diuretics response.
Journal ArticleDOI
The kidney in heart failure: an update.
Kevin Damman,Jeffrey M. Testani +1 more
TL;DR: An updated classification of the cardiorenal syndrome that incorporates recent evidence and points towards areas of interest and uncertainties, and areas where progress is needed could facilitate the search for preventive and treatment strategies that can preserve renal function and associated outcome in patients with HF.
Journal ArticleDOI
Automated, electronic alerts for acute kidney injury: a single-blind, parallel-group, randomised controlled trial
F. Perry Wilson,Michael G.S. Shashaty,Jeffrey M. Testani,Iram Aqeel,Yuliya Borovskiy,Susan S. Ellenberg,Harold I. Feldman,Hilda Fernandez,Yevgeniy Gitelman,Jennie Lin,Dan Negoianu,Chirag R. Parikh,Peter P. Reese,Richard Urbani,Barry D. Fuchs +14 more
TL;DR: Whether an automated electronic alert for acute kidney injury would reduce the severity of such injury and improve clinical outcomes in patients in hospital was investigated.