J
Jeffrey T. Borenstein
Researcher at Charles Stark Draper Laboratory
Publications - 255
Citations - 16412
Jeffrey T. Borenstein is an academic researcher from Charles Stark Draper Laboratory. The author has contributed to research in topics: Drug delivery & Silicon. The author has an hindex of 54, co-authored 243 publications receiving 15221 citations. Previous affiliations of Jeffrey T. Borenstein include Brigham and Women's Hospital & Amgen.
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Microscale technologies for tissue engineering and biology
TL;DR: An overview of the use of microfluidics, surface patterning, and patterned cocultures in regulating various aspects of cellular microenvironment is discussed, as well as the application of these technologies in directing cell fate and elucidating the underlying biology.
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Engineering substrate topography at the micro- and nanoscale to control cell function.
TL;DR: The use of in vitro synthetic cell-nanotopography interactions to control cell behavior and influence complex cellular processes, including stem-cell differentiation and tissue organization are reviewed.
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Accordion-like honeycombs for tissue engineering of cardiac anisotropy.
George C. Engelmayr,Mingyu Cheng,Christopher J. Bettinger,Jeffrey T. Borenstein,Robert Langer,Lisa E. Freed +5 more
TL;DR: Accordion-like honeycombs can overcome principal structural-mechanical limitations of previous scaffolds, promoting the formation of grafts with aligned heart cells and mechanical properties more closely resembling native myocardium.
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Anemia is associated with worse symptoms, greater impairment in functional capacity and a significant increase in mortality in patients with advanced heart failure.
Tamara B. Horwich,Gregg C. Fonarow,Michele A. Hamilton,W. Robb MacLellan,Jeffrey T. Borenstein +4 more
TL;DR: In chronic HF, relatively mild degrees of anemia are associated with worsened symptoms, functional status and survival, and low Hb proved to be an independent predictor of mortality.
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The prevalence, impairment, impact, and burden of premenstrual dysphoric disorder (PMS/PMDD)
TL;DR: It is demonstrated here that the burden of PMS/PMDD as well as the disability adjusted life years lost due to this repeated-cyclic disorder is in the same magnitude as major recognized disorders.