J
Jennifer M. Heemstra
Researcher at Emory University
Publications - 86
Citations - 1788
Jennifer M. Heemstra is an academic researcher from Emory University. The author has contributed to research in topics: Aptamer & RNA. The author has an hindex of 23, co-authored 72 publications receiving 1442 citations. Previous affiliations of Jennifer M. Heemstra include Georgia Institute of Technology & Harvard University.
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Journal ArticleDOI
Temporal Control of Aptamer Biosensors Using Covalent Self-Caging To Shift Equilibrium.
TL;DR: It is demonstrated that nature's self-caging approach can be effectively applied to non-natural receptors to provide precise temporal control over function and envision that this will be of especially high utility for deploying aptamer sensors in biological environments.
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Fluorescent RNA labeling using self-alkylating ribozymes.
Ashwani Sharma,Joshua J. Plant,Alexandra E. Rangel,Kirsten N. Meek,April J. Anamisis,Julie Hollien,Jennifer M. Heemstra +6 more
TL;DR: This work proposes a novel strategy in which a ribozyme acts to promote self-alkylation with a fluorophore, providing a robust, covalent linkage between the RNA and the fluorophile, and demonstrates that labeling is specific to the ribo enzyme sequences, as FIA does not react nonspecifically with RNA.
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Accelerating Strain-Promoted Azide–Alkyne Cycloaddition Using Micellar Catalysis
Grant I. Anderton,Alyssa S. Bangerter,Tyson C. Davis,Zhiyuan Feng,Aric J. Furtak,Jared O. Larsen,Triniti L. Scroggin,Jennifer M. Heemstra +7 more
TL;DR: Micellar catalysis can provide higher conjugation yields in reduced time when using hydrophobic SPAAC reagents, and is demonstrated to be successfully applied to hydrophilic biomolecules.
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Helix stabilization through pyridinium–π interactions
TL;DR: Intramolecular cation-pi interactions between a methyl pyridinium ion and a phenyl ring stabilize the folded structure of a phenyleneethynylene oligomer.
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Controlling self‐assembly of DNA‐polymer conjugates for applications in imaging and drug delivery
TL;DR: These investigations have laid the framework for using DNA-polymer conjugates in drug delivery, cellular imaging, and other applications in materials science and chemistry.