J
Jennifer Pham
Researcher at Children's Hospital Los Angeles
Publications - 1
Citations - 29
Jennifer Pham is an academic researcher from Children's Hospital Los Angeles. The author has contributed to research in topics: Proto-oncogene tyrosine-protein kinase Src & Cell adhesion molecule. The author has an hindex of 1, co-authored 1 publications receiving 13 citations.
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Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia.
Eun Ji Gang,Hye Na Kim,Yao-Te Hsieh,Yongsheng Ruan,Heather Ogana,Solomon Lee,Jennifer Pham,Huimin Geng,Eugene Park,Lars Klemm,Cheryl L. Willman,William L. Carroll,Steven D. Mittelman,Etan Orgel,Matthew J. Oberley,Chintan Parekh,Hisham Abdel-Azim,Deepa Bhojwani,Alan S. Wayne,Adèle De Arcangelis,Elisabeth Georges-Labouesse,Elizabeth Wayner,Halvard Bonig,Halvard Bonig,Aspram Minasyan,Johanna ten Hoeve,Thomas G. Graeber,Markus Müschen,Nora Heisterkamp,Yong-Mi Kim +29 more
TL;DR: The data support α6 as a novel therapeutic target for ALL by demonstrating that in vivo deletion of α6 in combination with tyrosine kinase inhibitor (TKI) treatment was more effective in eradicating ALL than treatment with a TKI (nilotinib) alone.