Jennifer R Chao

TL;DR: It is shown that lactate can suppress consumption of glucose by the retinal pigment epithelium, and this framework for understanding metabolic relationships in the vertebrate retina provides new insights into the underlying causes of retinal disease and age-related vision loss.

TL;DR: A user-guided segmentation method is proposed to perform the segmentation of retinal layers and features in OCT images by interactively navigating three-dimensional OCT images and demonstrating the reliability and efficiency of this method.

TL;DR: OCTA with motion tracking through an auxiliary real-time line scan ophthalmoscope is reported that is clinically feasible to image functional retinal vasculature in patients, with a coverage of more than 60 degrees of retina while still maintaining high definition and resolution.

TL;DR: Using 13C metabolic flux analysis in human RPE cells, it is found that RPE has an exceptionally high capacity for reductive carboxylation, a metabolic pathway that has recently garnered significant interest because of its role in cancer cell survival.

TL;DR: Chao et al. as mentioned in this paper showed that human ES cell-derived retinal neurons injected into the sub-macular space of a squirrel monkey survive at least 3 months postinjection without immunosuppression.