J
Jennifer S. Temel
Researcher at Harvard University
Publications - 386
Citations - 24692
Jennifer S. Temel is an academic researcher from Harvard University. The author has contributed to research in topics: Palliative care & Randomized controlled trial. The author has an hindex of 62, co-authored 337 publications receiving 19875 citations. Previous affiliations of Jennifer S. Temel include University of New Mexico & University of Southern California.
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Journal ArticleDOI
Early Palliative Care for Patients with Metastatic Non–Small-Cell Lung Cancer
Jennifer S. Temel,Joseph A. Greer,Alona Muzikansky,Emily R. Gallagher,Sonal Admane,Vicki A. Jackson,Constance Dahlin,Craig D. Blinderman,Juliet Jacobsen,William F. Pirl,J. Andrew Billings,Thomas J. Lynch +11 more
TL;DR: Among patients with metastatic non-small-cell lung cancer, early palliative care led to significant improvements in both quality of life and mood and, as compared with patients receiving standard care, patients received less aggressive care at the end of life but longer survival.
Journal ArticleDOI
Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors
Lecia V. Sequist,Belinda A. Waltman,Dora Dias-Santagata,Subba R. Digumarthy,Alexa B. Turke,Panos Fidias,Kristin Bergethon,Alice T. Shaw,Scott N. Gettinger,Arjola K. Cosper,Sara Akhavanfard,Rebecca S. Heist,Jennifer S. Temel,James G. Christensen,John C. Wain,Thomas J. Lynch,Kathy Vernovsky,Eugene J. Mark,Michael Lanuti,A. John Iafrate,Mari Mino-Kenudson,Jeffrey A. Engelman +21 more
TL;DR: Detailed genetic and histological analysis of 37 patients with drug-resistant non–small cell lung cancers carrying EGFR mutations provides new insights into the shifting sands of drug resistance evolution in lung cancers and suggests that serial biopsies may be essential in the quest to reverse or even prevent the development ofdrug resistance.
Journal ArticleDOI
Integration of Palliative Care Into Standard Oncology Care: American Society of Clinical Oncology Clinical Practice Guideline Update
Betty Ferrell,Jennifer S. Temel,Sarah Temin,Erin R. Alesi,Tracy A. Balboni,Ethan Basch,Janice Firn,Judith A. Paice,Jeffrey Peppercorn,Tanyanika Phillips,Ellen Stovall,Camilla Zimmermann,Thomas J. Smith +12 more
TL;DR: The guideline update reflects changes in evidence since the previous guideline and inpatients and outpatients with advanced cancer should receive dedicated palliative care services, early in the disease course, concurrent with active treatment.
Journal ArticleDOI
Longitudinal Perceptions of Prognosis and Goals of Therapy in Patients With Metastatic Non–Small-Cell Lung Cancer: Results of a Randomized Study of Early Palliative Care
Jennifer S. Temel,Joseph A. Greer,Joseph A. Greer,Joseph A. Greer,Sonal Admane,Sonal Admane,Sonal Admane,Emily R. Gallagher,Emily R. Gallagher,Emily R. Gallagher,Vicki A. Jackson,Vicki A. Jackson,Vicki A. Jackson,Thomas J. Lynch,Thomas J. Lynch,Thomas J. Lynch,Inga T. Lennes,Inga T. Lennes,Inga T. Lennes,C. M. Dahlin,C. M. Dahlin,C. M. Dahlin,William F. Pirl,William F. Pirl,William F. Pirl +24 more
TL;DR: Early palliative care significantly improves patient understanding of prognosis over time, which may impact decision making about care near the end of life.
Journal ArticleDOI
Effects of Early Integrated Palliative Care in Patients With Lung and GI Cancer: A Randomized Clinical Trial
Jennifer S. Temel,Joseph A. Greer,Areej El-Jawahri,William F. Pirl,Elyse R. Park,Vicki A. Jackson,Anthony L. Back,Mihir Kamdar,Juliet Jacobsen,Eva Chittenden,Simone Rinaldi,Emily R. Gallagher,Justin Eusebio,Zhigang Li,Alona Muzikansky,David P. Ryan +15 more
TL;DR: For patients with newly diagnosed incurable cancers, early integrated PC improved quality of life and other salient outcomes, with differential effects by cancer type.