Jens Erik Nielsen-Kudsk

TL;DR: Guidelines and Expert Consensus Documents summarise and evaluate all currently available evidence on a particular issue with the aim to assist physicians in selecting the best management strategies for a typical patient, suffering from a given condition, taking into account the impact on outcome, as well as the risk/benefit ratio of particular diagnostic or therapeutic means.

TL;DR: Among patients with a PFO who had a cryptogenic stroke, the risk of subsequent ischemic stroke was lower among those assign to PFO closure combined with antiplatelet therapy than among those assigned to anti platelet therapy alone; however, PFOclosure was associated with higher rates of device complications and atrial fibrillation.

TL;DR: In this multicentre study, LAAO with the ACP showed high procedural success and a favourable outcome for the prevention of AF-related thromboembolism and modification in antithrombotic therapy after LAAo may result in reduction of bleeding events.

TL;DR: PH is associated with worse survival in COPD, but PH does not influence the prognosis after lung transplantation, and both hypoxemia and hypercapnia were associated with mPAP.

TL;DR: GLP-1 infusion increased circulating insulin levels and reduced plasma glucose concentration but had no major cardiovascular effects in patients without diabetes but with compensated HF, and calls for caution in patients Without Diabetes but with HF.