J
Jeremy S. Rossman
Researcher at University of Kent
Publications - 39
Citations - 2370
Jeremy S. Rossman is an academic researcher from University of Kent. The author has contributed to research in topics: Virus & Membrane curvature. The author has an hindex of 17, co-authored 35 publications receiving 1992 citations. Previous affiliations of Jeremy S. Rossman include Uniformed Services University of the Health Sciences & Howard Hughes Medical Institute.
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Journal ArticleDOI
Curvature Sensing by a Viral Scission Protein
TL;DR: The results show that the M2AH senses membrane curvature and suggest that the AH domain may localize the protein at the viral neck where it can then mediate membrane scission and the release of budding viruses.
Journal ArticleDOI
Autophagy diminishes the early interferon-β response to influenza A virus resulting in differential expression of interferon-stimulated genes.
Brieuc Perot,Jeremy Boussier,Nader Yatim,Nader Yatim,Jeremy S. Rossman,Molly A. Ingersoll,Molly A. Ingersoll,Matthew L. Albert,Matthew L. Albert,Matthew L. Albert +9 more
TL;DR: Induction of autophagy by IAV infection reduces ISG expression in infected cells by limiting IFN-β expression, which may benefit viral replication and spread.
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Cholesterol Alters the Orientation and Activity of the Influenza Virus M2 Amphipathic Helix in the Membrane.
Agnieszka Martyna,Basma Bahsoun,Jesper J. Madsen,Frederic St. J.S. Jackson,Matthew D. Badham,Gregory A. Voth,Jeremy S. Rossman +6 more
TL;DR: Cholesterol regulates M2 membrane scission by precisely modulating M2AH positioning within the membrane, which has implications for the understanding of many of amphipathic-helix-driven cellular budding processes that occur in specific lipid environments.
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Sterol Uptake by an Alkali-β-Cyclodextrin Metal–Organic Framework
Barry A. Blight,Barry A. Blight,Towseef I. Ahmad,Helena J. Shepherd,Christopher S. Jennings,Livia I. Ferland,Simon J. Teat,Jeremy S. Rossman +7 more
TL;DR: The β-Cyclodextrin is well-known in cellular biology for its ability to moderate cholesterol levels in lipid bilayer membranes, but its use in extended network solids remains elusive due to the low symmetr...
Journal ArticleDOI
Intravirion cohesion of matrix protein M1 with ribonucleocapsid is a prerequisite of influenza virus infectivity.
TL;DR: The data suggest that the influenza virus has an asymmetric structure where the M1-mediated organization of the RNP inside the virion is a prerequisite for infectious entry into target cell.