J
Jérôme Le Chenadec
Researcher at French Institute of Health and Medical Research
Publications - 40
Citations - 1963
Jérôme Le Chenadec is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Viral load & Pregnancy. The author has an hindex of 20, co-authored 38 publications receiving 1797 citations. Previous affiliations of Jérôme Le Chenadec include Institut national d'études démographiques & University of Paris-Sud.
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Journal ArticleDOI
Mother-to-child HIV transmission despite antiretroviral therapy in the ANRS French Perinatal Cohort.
Josiane Warszawski,Roland Tubiana,Jérôme Le Chenadec,Stéphane Blanche,Jean-Paul Teglas,Catherine Dollfus,Albert Faye,Marianne Burgard,Christine Rouzioux,Laurent Mandelbrot,Anrs French Perinatal Cohort +10 more
TL;DR: Low maternal plasma viral load is the key factor for preventing mother-to-child HIV-1 transmission from mothers receiving antenatal antiretroviral therapy, and benefits in terms of MTCT reduction may be expected from early antireTroviral prophylaxis.
Journal ArticleDOI
No Perinatal HIV-1 Transmission From Women With Effective Antiretroviral Therapy Starting Before Conception
Laurent Mandelbrot,Roland Tubiana,Jérôme Le Chenadec,Catherine Dollfus,Albert Faye,Emmanuelle Pannier,Sophie Matheron,Marie-Aude Khuong,Valérie Garrait,Véronique Reliquet,Alain Devidas,Alain Berrebi,Christine Allisy,Christophe Elleau,Cédric Arvieux,Christine Rouzioux,Josiane Warszawski,Stéphane Blanche +17 more
TL;DR: Perinatal HIV-1 transmission is virtually zero in mothers who start ART before conception and maintain suppression of plasma VL.
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Perinatal antiretroviral treatment and hematopoiesis in HIV-uninfected infants.
TL;DR: Zidovudine administered during the perinatal period may result in a small but significant and durable effect on hematopoïesis up to the age of 18 months.
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Early versus Deferred Antiretroviral Multidrug Therapy in Infants Infected with HIV Type 1
Albert Faye,Jérôme Le Chenadec,Catherine Dollfus,Isabelle Thuret,Danièle Douard,Ghislaine Firtion,Eric Lachassinne,Martine Levine,Joelle Nicolas,Fabrice Monpoux,Joëlle Tricoire,Christine Rouzioux,Marc Tardieu,Marie Jeanne Mayaux,Stéphane Blanche +14 more
TL;DR: Infants who received multidrug therapy before 6 months of age did not have the early-onset severe form of childhood HIV disease, and further studies are needed to find accurate early markers of disease progression in this age group.
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HIV-1 virological remission lasting more than 12 years after interruption of early antiretroviral therapy in a perinatally infected teenager enrolled in the French ANRS EPF-CO10 paediatric cohort: a case report
Pierre Frange,Pierre Frange,Albert Faye,Véronique Avettand-Fenoel,Véronique Avettand-Fenoel,Erianna Bellaton,Diane Descamps,Mathieu Angin,Annie David,Sophie Caillat-Zucman,Gilles Peytavin,Catherine Dollfus,Jérôme Le Chenadec,Josiane Warszawski,Christine Rouzioux,Christine Rouzioux,Asier Sáez-Cirión +16 more
TL;DR: Findings from this case suggest that long-term HIV-1 remission is possible in perinatally infected children who receive treatment early, with characteristics similar to those reported in adult HIV post-treatment controllers.