Jessica A. Thompson

TL;DR: This overview clearly illustrates that bacterial communication is far more complex than initially thought and delivers a clear distinction between signals that are quorum sensing dependent and those relying on alternative factors for their production.

TL;DR: A comprehensive review of the discovery and early characterization of AI-2, current developments in signal detection, transduction and regulation, and the major studies investigating the phenotypes regulated by this molecule is presented.

TL;DR: This work engineered the enteric bacterium, Escherichia coli, to manipulate the levels of the interspecies quorum sensing signal, autoinducer-2 (AI-2), in the mouse intestine and investigated the effect upon antibiotic-induced gut microbiota dysbiosis.

TL;DR: This work reports the development of a reporter system based on fluorescence dilution that enables direct quantification of the replication dynamics of Salmonella enterica serovar Typhimurium in murine macrophages at both the population and single-cell level and finds that, upon entry into macrophage, many bacteria do not replicate, but appear to enter a dormant-like state.

TL;DR: A strain carrying a deletion in spvC is constructed and it is shown that the strain is attenuated for systemic virulence in mice and has phosphothreonine lyase activity on full‐length phospho‐Erk (pErk) and a synthetic 13‐amino‐acidospho‐peptide containing the TXY motif.