J
Jessica Ledesma
Researcher at Scripps Research Institute
Publications - 5
Citations - 945
Jessica Ledesma is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Candidate gene & Locus (genetics). The author has an hindex of 5, co-authored 5 publications receiving 915 citations. Previous affiliations of Jessica Ledesma include Scripps Institution of Oceanography.
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Journal ArticleDOI
Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases
Kermit L. Carraway,Janet L. Weber,Michelle J. Unger,Jessica Ledesma,Naichen Yu,Martin Gassmann,Martin Gassmann,Cary Lai +7 more
TL;DR: The results indicate that NRG-1 andNRG-2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biochemical responses in cells.
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Genetic and physical mapping of the Lps locus: identification of the toll-4 receptor as a candidate gene in the critical region.
Alexander Poltorak,Irina Smirnova,Xiaolong He,Mu Ya Liu,Christophe Van Huffel,Dale Birdwell,E. Alejos,M. Silva,Xin Du,Patricia A. Thompson,Edward K. L. Chan,Jessica Ledesma,Bruce A. Roe,Sandra W. Clifton,Stefanie N. Vogel,Bruce Beutler +15 more
TL;DR: To identify gene candidates, nearly 40,000 sequencing runs were performed across the critical region, and Selective hybridization and exon trapping were also employed to identify genes throughout the "zero" region.
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Illumina mate-paired DNA sequencing-library preparation using Cre-Lox recombination
Filip Van Nieuwerburgh,Ryan Thompson,Jessica Ledesma,Dieter Deforce,Terry Gaasterland,Phillip Ordoukhanian,Steven R. Head +6 more
TL;DR: A mate-paired protocol for use with Illumina sequencing technology that uses Cre-Lox recombination instead of blunt end circularization is developed and a LoxP sequence is incorporated at the junction site, which allows screening reads for junctions without using a reference genome.
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Genome Sequence of Helicobacter heilmannii Sensu Stricto ASB1 Isolated from the Gastric Mucosa of a Kitten with Severe Gastritis.
Annemieke Smet,Filip Van Nieuwerburgh,Jessica Ledesma,Bram Flahou,Dieter Deforce,Richard Ducatelle,Freddy Haesebrouck +6 more
TL;DR: The genome sequence of Helicobacter heilmannii sensu stricto ASB1 is isolated from the gastric mucosa of a kitten with severe gastritis and will contribute to the identification of genes involved in the pathogen's virulence and carcinogenic properties.
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Erratum: Genetic and physical mapping of the Lps locus: Identification of the toll-4 receptor as a candidate gene in the critical region (Blood Cells, Molecules, and Diseases (1998) 24:3 (340-355))
Alexander Poltorak,Irina Smirnova,Xiaolong He,Mu Ya Liu,C. Van Huffel,Dale Birdwell,E. Alejos,M. Silva,Xin Du,Paul R. Thompson,Edward K. L. Chan,Jessica Ledesma,Bruce A. Roe,Sandra W. Clifton,Stefanie N. Vogel,Bruce Beutler +15 more