J
Jessica Rodenburg
Researcher at University of Amsterdam
Publications - 18
Citations - 1713
Jessica Rodenburg is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Familial hypercholesterolemia & Pravastatin. The author has an hindex of 14, co-authored 18 publications receiving 1614 citations. Previous affiliations of Jessica Rodenburg include Erasmus University Rotterdam.
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Journal ArticleDOI
Efficacy and safety of statin therapy in Children with familial hypercholesterolemia: A randomized controlled trial
Albert Wiegman,Barbara A. Hutten,Eric de Groot,Jessica Rodenburg,Henk D. Bakker,Harry R. Büller,Eric J.G. Sijbrands,John J.P. Kastelein +7 more
TL;DR: Two years of pravastatin therapy induced a significant regression of carotid atherosclerosis in children with familial hypercholesterolemia, with no adverse effects on growth, sexual maturation, hormone levels, or liver or muscle tissue.
Journal ArticleDOI
Arterial intima-media thickness in children heterozygous for familial hypercholesterolaemia
Albert Wiegman,Eric de Groot,Barbara A. Hutten,Jessica Rodenburg,Johan Gort,Henk D. Bakker,Eric J.G. Sijbrands,John J.P. Kastelein +7 more
TL;DR: Findings on multivariate analysis showed LDL cholesterol, age, and sex to be strong and independent predictors of intima-media thickness of heterozygous children with familial hypercholesterolaemia.
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Statin Treatment in Children With Familial Hypercholesterolemia. The Younger, the Better
Jessica Rodenburg,Maud N. Vissers,Albert Wiegman,A S Paul van Trotsenburg,Anouk van der Graaf,Eric de Groot,Frits A. Wijburg,John J.P. Kastelein,Barbara A. Hutten +8 more
TL;DR: It is shown for the first time that early initiation of statin therapy in children with familial hypercholesterolemia might be beneficial in the prevention of atherosclerosis in adolescence.
Journal ArticleDOI
Family History and Cardiovascular Risk in Familial Hypercholesterolemia. Data in More Than 1000 Children
Albert Wiegman,Jessica Rodenburg,Saskia de Jongh,Joep C. Defesche,Henk D. Bakker,John J.P. Kastelein,Eric J.G. Sijbrands +6 more
TL;DR: In FH families, HDL-C levels allow accurate diagnosis of FH in childhood and increased LDL-C and lipoprotein(a) and decreased HDL- C levels in children identify FH kindreds with the highest CVD risk.
Journal ArticleDOI
Oxidized low-density lipoprotein in children with familial hypercholesterolemia and unaffected siblings : Effect of pravastatin
Jessica Rodenburg,Maud N. Vissers,Albert Wiegman,Elizabeth R. Miller,Paul M. Ridker,Joseph L. Witztum,John J.P. Kastelein,Sotirios Tsimikas +7 more
TL;DR: Compared with unaffected siblings, children with FH are characterized by elevated levels of apoB-IC and IgM MDA-LDL autoantibodies.