A
Albert Wiegman
Researcher at University of Amsterdam
Publications - 117
Citations - 9818
Albert Wiegman is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Familial hypercholesterolemia & Medicine. The author has an hindex of 34, co-authored 95 publications receiving 8170 citations. Previous affiliations of Albert Wiegman include Oslo University Hospital & Erasmus University Rotterdam.
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Journal ArticleDOI
Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society
Børge G. Nordestgaard,M. John Chapman,Steve E. Humphries,Henry N. Ginsberg,Luis Masana,Olivier S. Descamps,Olov Wiklund,Robert A. Hegele,Frederick J. Raal,Joep C. Defesche,Albert Wiegman,Raul D. Santos,Gerald F. Watts,Klaus G. Parhofer,G. Kees Hovingh,Petri T. Kovanen,Catherine Boileau,Maurizio Averna,Jan Borén,Eric Bruckert,Alberico L. Catapano,Jan Albert Kuivenhoven,Jan Albert Kuivenhoven,P. Pajukanta,Kausik K. Ray,Anton F. H. Stalenhoef,Erik S.G. Stroes,Marja-Riitta Taskinen,Anne Tybjærg-Hansen +28 more
TL;DR: There is an urgent worldwide need for diagnostic screening together with early and aggressive treatment of this extremely high-risk condition, familial hypercholesterolaemia.
Journal ArticleDOI
Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society
Marina Cuchel,Eric Bruckert,Henry N. Ginsberg,Frederick J. Raal,Raul D. Santos,Robert A. Hegele,Jan Albert Kuivenhoven,Børge G. Nordestgaard,Olivier S. Descamps,Elisabeth Steinhagen-Thiessen,Anne Tybjærg-Hansen,Gerald F. Watts,Maurizio Averna,Catherine Boileau,Jan Borén,A.L. Catapano,Joep C. Defesche,G. Kees Hovingh,Steve E. Humphries,Petri T. Kovanen,Luis Masana,Päivi Pajukanta,Klaus G. Parhofer,Kausik K. Ray,Anton F. H. Stalenhoef,Erik S.G. Stroes,Marja-Riitta Taskinen,Albert Wiegman,Olov Wiklund,M. John Chapman +29 more
TL;DR: In this article, the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society (EAS) critically reviewed available data with the aim of providing clinical guidance for the recognition and management of HoFH.
Journal ArticleDOI
Familial Hypercholesterolaemia in Children and Adolescents: Gaining Decades of Life by Optimizing Detection and Treatment
Albert Wiegman,Samuel S. Gidding,Gerald F. Watts,M. John Chapman,Henry N. Ginsberg,Marina Cuchel,Leiv Ose,Maurizio Averna,Catherine Boileau,Jan Borén,Eric Bruckert,Alberico L. Catapano,Joep C. Defesche,Olivier S. Descamps,Robert A. Hegele,G. Kees Hovingh,Steve E. Humphries,Petri T. Kovanen,Jan Albert Kuivenhoven,Luis Masana,Børge G. Nordestgaard,Päivi Pajukanta,Klaus G. Parhofer,Frederick J. Raal,Kausik K. Ray,Raul D. Santos,Anton F. H. Stalenhoef,Elisabeth Steinhagen-Thiessen,Erik S.G. Stroes,Marja-Riitta Taskinen,Marja-Riitta Taskinen,Anne Tybjærg-Hansen,Olov Wiklund +32 more
TL;DR: This consensus paper aims to improve awareness of the need for early detection and management of FH children by recommending cascade screening of families using a combined phenotypic and genotypic strategy.
Journal ArticleDOI
Efficacy and safety of statin therapy in Children with familial hypercholesterolemia: A randomized controlled trial
Albert Wiegman,Barbara A. Hutten,Eric de Groot,Jessica Rodenburg,Henk D. Bakker,Harry R. Büller,Eric J.G. Sijbrands,John J.P. Kastelein +7 more
TL;DR: Two years of pravastatin therapy induced a significant regression of carotid atherosclerosis in children with familial hypercholesterolemia, with no adverse effects on growth, sexual maturation, hormone levels, or liver or muscle tissue.
Journal ArticleDOI
Measurement of Arterial Wall Thickness as a Surrogate Marker for Atherosclerosis
Eric de Groot,G. Kees Hovingh,Albert Wiegman,Patrick Duriez,Andries J. Smit,Jean-Charles Fruchart,John J.P. Kastelein +6 more
TL;DR: Results are presented from a study that estimated atherosclerosis progression from childhood into old age by measuring intima-media thickness in subjects with familial hypercholesterolemia compared with healthy controls.