J
Ji-Xin Tang
Researcher at Chinese Academy of Sciences
Publications - 25
Citations - 432
Ji-Xin Tang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Medicine & Sertoli cell. The author has an hindex of 11, co-authored 16 publications receiving 276 citations.
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Journal ArticleDOI
Loss of Gata4 in Sertoli cells impairs the spermatogonial stem cell niche and causes germ cell exhaustion by attenuating chemokine signaling
Su-Ren Chen,Ji-Xin Tang,Jin-Mei Cheng,Jian Li,Cheng Jin,Xiao-Yu Li,Shou-Long Deng,Yan Zhang,Xiu-Xia Wang,Yi-Xun Liu +9 more
TL;DR: A novel role for GATA4 is revealed in controlling the SSC niche via the transcriptional regulation of chemokine signaling shortly after birth through deletion of Gata4 in Sertoli cells.
Journal ArticleDOI
Cyclin B2 can compensate for Cyclin B1 in oocyte meiosis I
Jian Li,Jian Li,Ji-Xin Tang,Jin-Mei Cheng,Bian Hu,Bian Hu,Yu-Qian Wang,Batool Aalia,Xiao-Yu Li,Cheng Jin,Xiu-Xia Wang,Shou-Long Deng,Yan Zhang,Su-Ren Chen,Wei-Ping Qian,Qing-Yuan Sun,Xing-Xu Huang,Xing-Xu Huang,Yi-Xun Liu +18 more
TL;DR: A hidden compensatory mechanism between Cyclin B1 and cyclin B2 in regulating MPF and oocyte meiotic resumption is revealed and is revealed to be a prerequisite for MPF activation in oocytes.
Journal ArticleDOI
Melatonin promotes development of haploid germ cells from early developing spermatogenic cells of Suffolk sheep under in vitro condition
Shou-Long Deng,Su-Ren Chen,Zhi-Peng Wang,Yan Zhang,Ji-Xin Tang,Jian Li,Xiu-Xia Wang,Jin-Mei Cheng,Cheng Jin,Xiao-Yu Li,Bao-Lu Zhang,Kun Yu,Zhengxing Lian,Guoshi Liu,Yi-Xun Liu +14 more
TL;DR: In this study, it is observed that melatonin supplementation significantly enhanced the cultured SSCs differentiation into haploid germ cells and the in vitro‐generated sperms were functional and they were capable to fertilize oocytes.
Journal ArticleDOI
Requirement for CCNB1 in mouse spermatogenesis
Ji-Xin Tang,Jian Li,Jin-Mei Cheng,Bian Hu,Bian Hu,Tie-Cheng Sun,Xiao-Yu Li,Aalia Batool,Zhi-Peng Wang,Xiu-Xia Wang,Shou-Long Deng,Yan Zhang,Su-Ren Chen,Xing-Xu Huang,Xing-Xu Huang,Yi-Xun Liu +15 more
TL;DR: It is found that ablation of CCNB1 in gonocytes and spermatogonia led to mouse sterile caused by the male germ cells’ depletion, and results indicate thatCCNB1 is critically required for the proliferation of gonocyte and sPerMatogonia but may be redundant in meiosis of sperMatocytes in mouse sper matogenesis.
Journal ArticleDOI
Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development
TL;DR: De deleting Wt1 in Sertoli cells caused aberrant differentiation and proliferation of PMCs, FLCs and interstitial progenitor cells from embryo to newborn, leading to abnormal fetal testis interstitial development.