Y
Young-Tae Chang
Researcher at Pohang University of Science and Technology
Publications - 464
Citations - 21972
Young-Tae Chang is an academic researcher from Pohang University of Science and Technology. The author has contributed to research in topics: BODIPY & Induced pluripotent stem cell. The author has an hindex of 69, co-authored 449 publications receiving 18488 citations. Previous affiliations of Young-Tae Chang include University of Michigan & Aston University.
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Intracellular glutathione detection using MnO2-nanosheet-modified upconversion nanoparticles
TL;DR: The ability to monitor the glutathione concentration intracellularly may enable rational design of a convenient platform for targeted drug and gene delivery.
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RNA buffers the phase separation behavior of prion-like RNA binding proteins
Shovamayee Maharana,Jie Wang,Dimitrios K. Papadopoulos,Dimitrios K. Papadopoulos,Doris Richter,Andrey Pozniakovsky,Ina Poser,Marc Bickle,Sandra Rizk,Sandra Rizk,Jordina Guillén-Boixet,Titus M. Franzmann,Marcus Jahnel,Marcus Jahnel,Lara Marrone,Young-Tae Chang,Jared Sterneckert,Pavel Tomancak,Anthony A. Hyman,Simon Alberti +19 more
TL;DR: It is proposed that the nucleus is a buffered system in which high RNA concentrations keep RBPs soluble, and low RNA/protein ratios promote phase separation into liquid droplets, whereas high ratios prevent droplet formation in vitro.
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Discerning the Chemistry in Individual Organelles with Small-Molecule Fluorescent Probes.
TL;DR: This Review summarizes the existing fluorescent probes that target chemical/biological events within a single organelle and organelle-anchoring strategies are described and emphasized to inspire the design of new generations of fluorescent probes, before concluding with future prospects on the possible further development of chemical biology.
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Combinatorial Strategies in Fluorescent Probe Development
TL;DR: This poster presents a poster presented at the 2016 Singapore International Conference of the American Association for the Advancement of Science and Technology (A*STAR) entitled “Advances in Bioimaging Probe Development: Foundations of a scalable, scalable and reproducible Nanofiltration Probe for Matrix-based Assays.”
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RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation
Jordina Guillén-Boixet,Andrii Kopach,Alex S. Holehouse,Sina Wittmann,Marcus Jahnel,Marcus Jahnel,Raimund Schlüßler,Kyoohyun Kim,Irmela R.E.A. Trussina,Jie Wang,Daniel Mateju,Ina Poser,Shovamayee Maharana,Martine Ruer-Gruß,Doris Richter,Xiaojie Zhang,Young-Tae Chang,Jochen Guck,Alf Honigmann,Julia Mahamid,Anthony A. Hyman,Rohit V. Pappu,Simon Alberti,Simon Alberti,Titus M. Franzmann +24 more
TL;DR: It is proposed that condensation coupled to conformational rearrangements and heterotypic multivalent interactions may be a general principle underlying RNP granule assembly.