J
Jian Song
Researcher at Zhengzhou University
Publications - 27
Citations - 489
Jian Song is an academic researcher from Zhengzhou University. The author has contributed to research in topics: Chalcone & Tubulin. The author has an hindex of 9, co-authored 26 publications receiving 278 citations.
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Journal ArticleDOI
Design, synthesis and antiproliferative activity studies of novel dithiocarbamate-chalcone derivates.
Dong-Jun Fu,Sai-Yang Zhang,Ying-Chao Liu,Zhang Li,Jun-Ju Liu,Jian Song,Ruo-Han Zhao,Feng Li,Hui-Hui Sun,Hong-Min Liu,Yan-Bing Zhang +10 more
TL;DR: A series of dithiocarbamate-chalcone derivates were designed, synthesized and evaluated for antiproliferative activity against three selected cancer cell lines (EC-109, SK-N-SH and MGC-803) as mentioned in this paper.
Journal ArticleDOI
Mechanisms of synergistic neurotoxicity induced by two high risk pesticide residues - Chlorpyrifos and Carbofuran via oxidative stress.
TL;DR: The results showed CPF and CBF have a synergistic neurotoxicity on neural cell SK-N-SH and the toxicity remained on long-term low-dose condition.
Journal ArticleDOI
Design, Synthesis and Structure-Activity Relationships of Novel Chalcone-1,2,3-triazole-azole Derivates as Antiproliferative Agents
Sai-Yang Zhang,Dong-Jun Fu,Xiao-Xin Yue,Ying-Chao Liu,Jian Song,Hui-Hui Sun,Hong-Min Liu,Yan-Bing Zhang +7 more
TL;DR: A series of chalcone-1,2,3-triazole-azole hybrids were designed, synthesized and evaluated for their antiproliferative activity against three selected cancer cell lines (SK-N-SH, EC-109 and MGC-803) as discussed by the authors.
Journal ArticleDOI
Design and synthesis of formononetin-dithiocarbamate hybrids that inhibit growth and migration of PC-3 cells via MAPK/Wnt signaling pathways.
Dong-Jun Fu,Zhang Li,Jian Song,Ruo-Wang Mao,Ruo-Han Zhao,Ying-Chao Liu,Yu-Hui Hou,Jia-Huan Li,Jia-Jia Yang,Cheng-Yun Jin,Ping Li,Xiaolin Zi,Hong-Min Liu,Sai-Yang Zhang,Yan-Bing Zhang +14 more
TL;DR: A series of novel formononetin-dithiocarbamate derivatives were designed, synthesized and evaluated for antiproliferative activity against three selected cancer cell line (MGC-803, EC-109, PC-3) as mentioned in this paper.
Journal ArticleDOI
Design, synthesis and antiproliferative activity studies of 1,2,3-triazole–chalcones
Dong-Jun Fu,Sai-Yang Zhang,Ying-Chao Liu,Xiao-Xin Yue,Jun-Ju Liu,Jian Song,Ruo-Han Zhao,Feng Li,Hui-Hui Sun,Yan-Bing Zhang,Hong-Min Liu +10 more
TL;DR: The mechanism studies revealed that compound 12k inhibited the proliferation of SK-N-SH cancer cells by inducing apoptosis and arresting the cell cycle at the G1 phase.