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Jian-Xun Liu

Researcher at Peking Union Medical College

Publications -  157
Citations -  8345

Jian-Xun Liu is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Blood stasis & Ischemia. The author has an hindex of 29, co-authored 157 publications receiving 7270 citations. Previous affiliations of Jian-Xun Liu include Beijing University of Chinese Medicine & University of Sydney.

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Journal Article

Study on effect of weinaokang and bilobalide on autophagy and neurogenesis induced by focal cerebral ischemia reperfusion

TL;DR: WNK and its active compound bilobalide can inhibit neuron autophagy and improve Neurogenesis in ischemic peripheral area, suggesting that neurogenesis may be the intervention target for WNK to promote self-repairing of isChemic area.
Journal Article

[Effect and mechanism of huatuo zaizao extractum on focal cerebral ischemia/reperfusion-induced blood-brain barrier injury in rats].

TL;DR: Cell membrane coupling GRK2 may be the effective target of Huatuo Zaizao extractum, which could effectively recover cerebral micro-vascular endothelial edema and blood-brain barrier ultrastructure injury induced by I/R, reduce expression of functional (membrane coupling)GRK2, and inhibit expressions of MMP-2 and M MP-9.
Journal Article

[Study of rongban tongmai granule on anti-oxidant stress in atherosclerosis].

TL;DR: Rongban Tongmai granule can prevent atherosclerosis by antioxidative stress and correcting unbalance of redox by inhibit atherosclerotic lesion in aorta, decrease the level of MDA and LP(a) (P < 0.05) after treated for 8 weeks in serum, and increase the activity of SOD, GSH and NO content in the liver, as well as MDA was decreased.
Journal Article

Fat soluble constituents of the leaves of Vaccinium bracteatum Thunb

TL;DR: Four compounds were isolated from the fat soluble fraction of the leaves of Vaccinium bracteatum and identified as friedelin (I), epifriedelinol (II), beta-sitosterol(III) and ursolic acid(IV) by IR, NMR and MS.
Journal Article

[Protective effect of hawthorn leaf procyanidins on cardiomyocytes of neonatal rats subjected to simulated ischemia-reperfusion injury].

TL;DR: Hawthorn leaf procyanidins have a significant therapeutic effect on the simulated ischemia-reperfusion injury of cultured neonatal rat cardiomyocytes, which may relate to their anti-oxidation effects.