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Jian-Xun Liu

Researcher at Peking Union Medical College

Publications -  157
Citations -  8345

Jian-Xun Liu is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Blood stasis & Ischemia. The author has an hindex of 29, co-authored 157 publications receiving 7270 citations. Previous affiliations of Jian-Xun Liu include Beijing University of Chinese Medicine & University of Sydney.

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Journal ArticleDOI

By Activating Akt/eNOS Bilobalide B Inhibits Autophagy and Promotes Angiogenesis Following Focal Cerebral Ischemia Reperfusion.

Yongqiu Zheng, +7 more
- 01 Jan 2018 - 
TL;DR: It is found that intraperitoneal delivery of various Bilobalide doses during ischemia can protect against brain injury, as evidenced by reduced infarct size and improved neurological scores after surgery.
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Ginkgo biloba Extract Inhibits Astrocytic Lipocalin-2 Expression and Alleviates Neuroinflammatory Injury via the JAK2/STAT3 Pathway After Ischemic Brain Stroke.

Yehao Zhang, +10 more
- 16 May 2018 - 
TL;DR: EGB is demonstrated to mediate neuro inflammation, which protects against ischemic brain injury by inhibiting astrogliosis and suppresses neuroinflammation via the LCN2-JAK2/STAT3 pathway, providing insight into a promising therapeutic strategy for ischeMIC stroke.
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Development of liquid chromatography/mass spectrometry methods for the quantitative analysis of herbal medicine in biological fluids: a review.

Michael J. Gray, +4 more
- 01 Jan 2010 - 
TL;DR: The development of liquid chromatography-mass spectrometry and tandem MS/MS for the analysis of bioactive components and their metabolites of herbal medicines in biological fluids is reviewed with the aim of providing an overview of the current techniques and methods used.
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Magnesium lithospermate B is excreted rapidly into rat bile mostly as methylated metabolites, which are potent antioxidants.

Ying Zhang, +6 more
- 01 Jul 2004 - 
TL;DR: High-performance liquid chromatography revealed that four major metabolites with lower polarity were excreted into bile after intravenous and oral administration of MLB and suggested that they could undergo enterohepatic circulation in rats and may be largely responsible for the pharmacological effects of MLB.
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Baicalin attenuates proinflammatory cytokine production in oxygen-glucose deprived challenged rat microglial cells by inhibiting TLR4 signaling pathway

Jincai Hou, +8 more
- 01 Dec 2012 - 
TL;DR: The results show that baicalin can inhibit OGD-induced production of inflammatory factors in microglial cells by attenuating inflammatory factors and regulating the TLR4 signaling pathways.