J
Jiawei Guo
Researcher at Third Military Medical University
Publications - 20
Citations - 826
Jiawei Guo is an academic researcher from Third Military Medical University. The author has contributed to research in topics: Drug delivery & Drug carrier. The author has an hindex of 13, co-authored 17 publications receiving 428 citations.
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Journal ArticleDOI
A Proresolving Peptide Nanotherapy for Site-Specific Treatment of Inflammatory Bowel Disease by Regulating Proinflammatory Microenvironment and Gut Microbiota.
Chenwen Li,Yang Zhao,Juan Cheng,Jiawei Guo,Qixiong Zhang,Xiangjun Zhang,Jiong Ren,Fengchao Wang,Jun Huang,Houyuan Hu,Ruibing Wang,Jianxiang Zhang +11 more
TL;DR: A smart nanotherapy developed, which can release packaged Ac2‐26, in response to highly expressed reactive oxygen species (ROS) at diseased sites, reduces symptoms of inflammation, accelerates intestinal mucosal wound healing, reshapes the gut microbiota composition, and increases short‐chain fatty acid production.
Journal ArticleDOI
A Broad-Spectrum ROS-Eliminating Material for Prevention of Inflammation and Drug-Induced Organ Toxicity.
Lanlan Li,Jiawei Guo,Yuquan Wang,Yuquan Wang,Xiaoxing Xiong,Hui Tao,Jin Li,Yi Jia,Houyuan Hu,Jianxiang Zhang +9 more
TL;DR: A superoxidase dismutase/catalase‐mimetic material based on Tempol and phenylboronic acid pinacol ester simultaneously conjugated β‐cyclodextrin, which is capable of eliminating a broad spectrum of reactive oxygen species (ROS), is reported.
Journal ArticleDOI
Non-proinflammatory and responsive nanoplatforms for targeted treatment of atherosclerosis
Yin Dou,Yue Chen,Xiangjun Zhang,Xiaoqiu Xu,Yidan Chen,Jiawei Guo,Dinglin Zhang,Ruibing Wang,Xiaohui Li,Jianxiang Zhang +9 more
TL;DR: For the first time, the therapeutic advantages of nanomedicines responsive to mildly acidic or abnormally high ROS microenvironments for the treatment of atherosclerosis are demonstrated.
Journal ArticleDOI
Yeast Microcapsule-Mediated Targeted Delivery of Diverse Nanoparticles for Imaging and Therapy via the Oral Route.
Xing Zhou,Xiangjun Zhang,Xiangjun Zhang,Songling Han,Yin Dou,Mengyu Liu,Lin Zhang,Jiawei Guo,Qing Shi,Genghao Gong,Ruibing Wang,Jiang Hu,Xiaohui Li,Jianxiang Zhang +13 more
TL;DR: Through the intricate transportation route, nanoprobes or nanotherapies enveloped in YC can be preferentially delivered to desired targets, affording remarkably improved efficacies for the treatment of multiple diseases associated with inflammation.
Journal ArticleDOI
Bioresponsive drug delivery systems for the treatment of inflammatory diseases.
TL;DR: This review provides a brief introduction of the pathogenesis of inflammation, with an emphasis on representative inflammatory cells and mediators in inflammatory microenvironments that serve as pathological fundamentals for rational design of bioresponsive carriers.