J
Jiaxing Zhao
Researcher at Capital Normal University
Publications - 5
Citations - 87
Jiaxing Zhao is an academic researcher from Capital Normal University. The author has contributed to research in topics: Aptamer & Systematic evolution of ligands by exponential enrichment. The author has an hindex of 2, co-authored 5 publications receiving 40 citations.
Papers
More filters
Journal ArticleDOI
Selection of Group-Specific Phthalic Acid Esters Binding DNA Aptamers via Rationally Designed Target Immobilization and Applications for Ultrasensitive and Highly Selective Detection of Phthalic Acid Esters
Yu Han,Donglin Diao,Zhangwei Lu,Xiaoning Li,Qian Guo,Yumeng Huo,Qing Xu,You-Shan Li,Sheng-Li Cao,Jianchun Wang,Yuan Wang,Jiaxing Zhao,Zhongfeng Li,Miao He,Zhaofeng Luo,Xinhui Lou +15 more
TL;DR: For the first time, group-specific PAE-binding aptamers via rationally designed target immobilization are identified and offered the promise of convenient, low-cost detection of total PAEs.
Journal ArticleDOI
Speeding up in Vitro Discovery of Structure-Switching Aptamers via Magnetic Cross-Linking Precipitation.
Na Qiao,Jing Li,Xiao Wu,Donglin Diao,Jiaxing Zhao,Jiyuan Li,Xijiao Ren,Xiaofan Ding,Dihua Shangguan,Xinhui Lou +9 more
TL;DR: The application of the selected SSA in fluorescent detection of HSA in urine with diagnostic required sensitivity and dynamic range is demonstrated and it is expected that MCP-SELEX may be coupled with other selection methods to substantially accelerate aptamer discovery.
Journal ArticleDOI
Nanoscale Affinity Double Layer Overcomes the Poor Antimatrix Interference Capability of Aptamers.
TL;DR: In this article, a multiple-function interface, denoted as a nanoscale affinity double layer (NADL), is proposed to overcome the bottleneck of poor antimatrix interference capability of aptamers.
Journal ArticleDOI
PD-L1 aptamer isolation via Modular-SELEX and its applications in cancer cell detection and tumor tissue section imaging.
TL;DR: In this paper, a combination method, named Modular-SELEX (systematic evolution of ligands by exponential enrichment), which includes three sequentially performed modules: the affinity module, the specificity module, and the compatibility module.
Journal ArticleDOI
A highly specific aptamer probe targeting PD-L1 in tumor tissue sections: Mutation favors specificity
TL;DR: In this paper, a DNA aptamer that highly specifically binds Programmed Cell Death-ligand 1 (PD-L1) expressed on the surface of various cancer cells and multiple types of tissue sections was reported.