J
Jie Ren
Researcher at Beijing Institute of Genomics
Publications - 1
Citations - 71
Jie Ren is an academic researcher from Beijing Institute of Genomics. The author has contributed to research in topics: Heterochromatin & Adult stem cell. The author has an hindex of 1, co-authored 1 publications receiving 28 citations.
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SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer
Shijia Bi,Zunpeng Liu,Zeming Wu,Zehua Wang,Xiaoqian Liu,Si Wang,Jie Ren,Yan Yao,Weiqi Zhang,Moshi Song,Guang-Hui Liu,Jing Qu +11 more
TL;DR: It is found that SIRT7 expression declines during human mesenchymal stem cell (hMSC) aging and that Sirt7 deficiency accelerates senescence, highlighting how SIRT6 safeguards chromatin architecture to control innate immune regulation and ensure geroprotection during stem cell aging.