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Jih Ing Chuang

Researcher at National Cheng Kung University

Publications -  53
Citations -  3125

Jih Ing Chuang is an academic researcher from National Cheng Kung University. The author has contributed to research in topics: Melatonin & Neuroprotection. The author has an hindex of 28, co-authored 53 publications receiving 2907 citations. Previous affiliations of Jih Ing Chuang include University of Valladolid & University of Texas Health Science Center at San Antonio.

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A review of the evidence supporting melatonin's role as an antioxidant

TL;DR: Melatonin is remarkably potent in protecting against free radical damage induced by a variety of means, and DNA damage resulting from either the exposure of animals to the chemical carcinogen safrole or to ionizing radiation is markedly reduced when melatonin is co‐administered.
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Running exercise protects the substantia nigra dopaminergic neurons against inflammation-induced degeneration via the activation of BDNF signaling pathway

TL;DR: Results show that running exercise protects DA neurons against inflammation-induced insults, and the neuroprotective effects of Ex are not due to the modulation of inflammation status, but rather to the activation of the BDNF-TrkB signaling pathway.
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Differential effects of treadmill running and wheel running on spatial or aversive learning and memory: roles of amygdalar brain-derived neurotrophic factor and synaptotagmin I.

TL;DR: The notion that different forms of exercise induce neuroplasticity changes in different brain regions, and thus exert diverse effects on various forms of learning and memory, is supported.
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EFFECT OF MELATONIN ON NF‐κB DNA‐BINDING ACTIVITY IN THE RAT SPLEEN

TL;DR: In vivo results indicate that the normal night time rise which can be expected for melatonin may be associated with increased NF‐κB DNA binding activity in the spleen, and suggest that the melatonin could potentially act to modulate spleen function and/or the immune system by regulating the NF‐ κB DNA bound activity.
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Novel magnetic/ultrasound focusing system enhances nanoparticle drug delivery for glioma treatment

TL;DR: Combining these techniques significantly improved the delivery of 1,3-bis(2-chloroethyl)-1-nitrosourea to rodent gliomas and suppressed tumor progression without damaging the normal regions of the brain.