J
Jihua Wang
Researcher at Indiana University
Publications - 94
Citations - 2186
Jihua Wang is an academic researcher from Indiana University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 19, co-authored 59 publications receiving 1520 citations.
Papers
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Journal ArticleDOI
Improving prediction of secondary structure, local backbone angles, and solvent accessible surface area of proteins by iterative deep learning.
Rhys Heffernan,Kuldip K. Paliwal,James Lyons,Abdollah Dehzangi,Alok Sharma,Jihua Wang,Abdul Sattar,Yuedong Yang,Yaoqi Zhou +8 more
TL;DR: The accuracy of the iterative use of predicted secondary structure and backbone torsion angles and dihedrals based on Cα atoms is higher than those of model structures from current state-of-the-art techniques, suggesting the potentially beneficial use of these predicted properties for model assessment and ranking.
Journal ArticleDOI
Real-time reliable determination of binding kinetics of DNA hybridization using a multi-channel graphene biosensor
Shicai Xu,Jian Zhan,Baoyuan Man,Shouzhen Jiang,Weiwei Yue,Shoubao Gao,Chengang Guo,Hanping Liu,Zhenhua Li,Jihua Wang,Yaoqi Zhou +10 more
TL;DR: It is demonstrated that a graphene single-crystal domain patterned into multiple channels can measure time- and concentration-dependent DNA hybridization kinetics and affinity reliably and sensitively, with a detection limit of 10 pM for DNA.
Journal ArticleDOI
Sixty-five years of the long march in protein secondary structure prediction: the final stretch?
Yuedong Yang,Jianzhao Gao,Jihua Wang,Rhys Heffernan,Jack Hanson,Kuldip K. Paliwal,Yaoqi Zhou +6 more
TL;DR: The time has come to finish off the final stretch of the long march towards protein secondary structure prediction as more powerful deep learning methods with improved capability of capturing long-range interactions begin to emerge as the next generation of techniques forsecondary structure prediction.
Book ChapterDOI
SPIDER2: A Package to Predict Secondary Structure, Accessible Surface Area, and Main-Chain Torsional Angles by Deep Neural Networks
Yuedong Yang,Rhys Heffernan,Kuldip K. Paliwal,James Lyons,Abdollah Dehzangi,Alok Sharma,Alok Sharma,Jihua Wang,Abdul Sattar,Abdul Sattar,Yaoqi Zhou +10 more
TL;DR: A newly developed method SPIDER2 is described that utilizes three iterations of deep learning neural networks to improve the prediction accuracy of several structural properties simultaneously and provides state-of-the-art, all-in-one accurate prediction of local structure and solvent accessible surface area.
Journal ArticleDOI
Local hot charge density regulation: Vibration-free pyroelectric nanogenerator for effectively enhancing catalysis and in-situ surface enhanced Raman scattering monitoring
Chonghui Li,Shicai Xu,Jing Yu,Zhen Li,Weifeng Li,Jihua Wang,Aihua Liu,Baoyuan Man,Shikuan Yang,Chao Zhang +9 more
TL;DR: Wang et al. as mentioned in this paper designed a pyroelectric nanogenerator by absorbing optical energy as surface enhanced Raman scattering (SERS) substrate for in-situ monitoring the complete oxidation reaction from 4-aminothiophenol (4-ATP) to 4-nitrothiophenolate (NTP) and the oxygen reduction reaction (ORR) intermediates.