Jin-Sung Park

TL;DR: Differently from the previously constructed embryonic stem cell-derived Plac8 knockout mouse that contains a neomycin resistance cassette, this knockout mouse model is free from a negative selection marker or other external insertions, which will be useful in future studies aimed at elucidating the multi-functional and physiological roles of PLAC8 in various diseases, without interference from exogenous foreign DNA.

TL;DR: Assessment of subchronic toxicity of DM extract by oral administration in rats revealed unremarkable treatment-related findings with respect to food/water consumption, body weight, mortality, urinalysis, hematology, serum biochemistry, necropsy, organ weight and histopathology.

TL;DR: It is shown that single heterozygous ATP13A2 mutations (sHTZ) cause mitochondrial dysfunction and Zn dyshomeostasis in skin fibroblasts from sHTZ carriers, and zinc transporters zinc transporter 1 (ZnT1), and ZRT/IRT-related protein1 (ZIP1) were greatly reduced in s HTZ cells, supporting the notion of dysregulated Zn metabolism.

TL;DR: Results indicate that gold thread implantation can be an effective way to promote hair re-growth although further confirmatory study is needed for more information on therapeutic mechanisms and long-term safety.

TL;DR: FCPE did not cause systemic and genetic toxicity in model systems at the tested dose levels, and a guideline for safe consumption of C. sunki peel in human is suggested.