Showing papers in "Journal of Ethnopharmacology in 2019"

TL;DR: Current evidence indicates anti-inflammatory activity in EORO, supporting its ethnopharmacological uses in inflammatory-related diseases, and potential future applications.

TL;DR: It is demonstrated that RPD had effect on ulcerative colitis, which was related to regulating gut microbiota, especially Butyricicoccus pullicaecorum, and SCFAs to restore the gut Th17/Treg homeostasis.

TL;DR: The chromatographic technique remains the most extensively used approach for the identification or quantitation of PNSs, coupled with different detectors, among which the difference mainly lies in their sensitivity and specificity for analyzing various compounds.

TL;DR: Combining network pharmacology with validation experimental results, the nourishing blood effect of DBD might be manifested by the dual mechanism of enhancing immunity and promoting hematopoiesis.

TL;DR: Current therapeutic strategies have proven that the goal of the traditional oriental medicine principle of increasing bodily fluids is a relevant approach for reducing the development of hearing loss by improving microcirculation in the blood-labyrinth barrier and increasing cochlear blood flow.

TL;DR: Glycosides improved neurological dysfunction, alleviated neuronal damage, and inhibited neuronal pyroptosis after cerebral I/R injury, and exert neuroprotective effects by inhibiting pyroPTosis of neurons after cerebral ischemia reperfusion injury.

TL;DR: Findings on medicinal plants with both anti-diabetic and anti-hypertensive effects reported in same experimental study are reviewed to facilitate the development of dual-acting therapies against diabetes and hypertension.

TL;DR: Most plant products with consistently reported anti-cancer efficacy contains high levels of polyphenols or other potent antioxidants and their mechanisms of action correlate to that reported for isolated antioxidants in the context of cancer, suggesting that natural products may indeed become the panacea against this chronic disease.

TL;DR: DS has an anti-atherosclerotic ability to lower lipid concentrations and to protect endothelial function, and it also has anti-inflammatory activity.

TL;DR: RCAE attenuated HH-induced brain injury by regulating apoptosis and mitochondrial energy metabolism via the HIF-1α/microRNA 210/ISCU1/2 (COX10) signaling pathway.

TL;DR: There is a need for systematic evaluation of the more commonly used plants to confirm their antidiabetic activity, identify possible mechanimss of action, and recommend best use.

TL;DR: These findings demonstrate for the first time the correlation between the anti-inflammatory activity of SCF4 and TLR-mediated NF-κB and MAPK signaling pathways in LPS-stimulated RAW264.7 macrophage cells, suggesting that the non-aqueous extract of S. crispa could be applied as a promising natural product for the prevention and treatment of inflammatory diseases.

TL;DR: The interaction with gut microbiota is still not fully investigated for many herbal drugs traditionally used for gastrointestinal disorders, which offers a vast field for future research.

TL;DR: Zanthoxylum armatum DC possesses several medicinal properties and has been commonly used in different indigenous medicinal practices to cure several diseases because of its stomachic, carminative and anthelmintic properties.

TL;DR: Magnoliae Officinalis Cortex is an essential traditional Chinese medicine with pharmacological activities that mainly affect the digestive system, nervous system and cardiovascular and cerebrovascular systems, and a review summarises its botany, ethnopharmacology, phytochemistry, pharmacology and toxicology.

TL;DR: Dendrobium cultivation has a great potential to link the commercial TCM industry together with initiatives of biodiversity conservation and both the artificial-sheltered cultivation and ecologically-friendly cultivation contribute to the conservation of Dendroium species.

TL;DR: The curzerene chemotype oil and E. uniflora oils can be indicated as drug candidates for anticancer activity of the lung, colon, stomach, and melanoma, with a real prospect to their subsequent phytotherapeutic development.

TL;DR: Low to very low quality evidences for the primary outcomes and sparse data for several safety outcomes, thus, warrant further research.

TL;DR: This review created the comparative and comprehensive feature of hepatotoxicity by herbal products, which provides reference data for the clinical applications and establishing pharmacovigilance system of herbs.

TL;DR: The study demonstrated that the synergy molecular mechanisms of BXD mainly involved three therapeutic modules including inhibiting inflammatory reaction, maintaining intestinal function and improving psychological regulation via the multicomponent-target interaction networks.

TL;DR: A new approach in ethnopharmacology is demonstrated by mapping plant usages to diseases prevalent in a community from old ethnobotanical travel reports, revealing the therapeutic potential of Caatinga species using cluster analysis.

TL;DR: Dragon's blood is a valuable source of bioactive compounds, mainly flavonoids and their oligomers, and its potential therapeutic effects on different diseases are attractive, such as the notable effect on cardiovascular diseases.

TL;DR: Results showed that XXT could notably correct lipid metabolism disorders, alleviate systematic inflammation, improve insulin sensitivity and reduce fat accumulation, and unraveled the molecular mechanism of XXT on the alleviation of dyslipidemia and fat heterotopic accumulation.

TL;DR: CISCFE treatment could effectively mitigate the D-galactose-induced hepatic and cerebral injury, and the underlying mechanism might be tightly related to the decreased oxidative stress, inflammation and apoptosis, indicating CISCFE might be an alternative and promising agent for the treatment of aging and age-associated brain and liver diseases.

TL;DR: This is the first report to investigate the antidepressant-like effects and underlying mechanisms of XYS from the perspective of brain metabolites and indicates that XYS significantly reversed the metabolic perturbation caused by CUMS.

TL;DR: This review aims to provide critical summary of the current evidence on A.biserrata, a widely used traditional Chinese medicine used for expelling wind, eliminating dampness, and terminating pain that has been proven as a valuable medicinal sources from traditional herb.

TL;DR: Coping was associated with high kratom consumption among regular kratom users in traditional, rural settings and higher scores on the coping domain was significantly associated with higher kratom Consumption.

TL;DR: The acetone extract of Typha capensis and its fractions had good anti-inflammatory and antioxidant activities, supporting the medicinal use of this species against inflammation.

TL;DR: Analysis of the constructed pharmacological networks results allowed for the prediction and interpretation of the multi-constituent, multi-target, and multi-pathway mechanisms of North African plants as potential source for supportive treatment of cancer where their potential molecular mechanism towards cancer-associated targets, biological processes and pathways were revealed.

TL;DR: This review article provides explicit information on traditional uses, phytochemistry, and pharmacological activities of selected Psoralea species and the possible trends and perspectives for future research on these plants are discussed.