J
Jinyong Choi
Researcher at La Jolla Institute for Allergy and Immunology
Publications - 5
Citations - 2117
Jinyong Choi is an academic researcher from La Jolla Institute for Allergy and Immunology. The author has contributed to research in topics: Cellular differentiation & Regulation of gene expression. The author has an hindex of 5, co-authored 5 publications receiving 649 citations. Previous affiliations of Jinyong Choi include Catholic University of Korea.
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Journal ArticleDOI
Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity.
Carolyn Rydyznski Moderbacher,Sydney I. Ramirez,Sydney I. Ramirez,Jennifer M. Dan,Jennifer M. Dan,Alba Grifoni,Kathryn M. Hastie,Daniela Weiskopf,Simon Bélanger,Robert K. Abbott,Christina K. Kim,Jinyong Choi,Yu Kato,Eleanor G. Crotty,Cheryl Kim,Stephen A. Rawlings,Jose Mateus,Longping V. Tse,April Frazier,Ralph S. Baric,Bjoern Peters,Jason A. Greenbaum,Erica Ollmann Saphire,Erica Ollmann Saphire,Davey M. Smith,Alessandro Sette,Alessandro Sette,Shane Crotty,Shane Crotty +28 more
TL;DR: A combined examination of all three branches of adaptive immunity at the level of SARS-CoV-2-specific CD4+ and CD8+ T cell and neutralizing antibody responses in acute and convalescent subjects suggested roles for both CD4 plus T cells in protective immunity in COVID-19.
Journal ArticleDOI
Antigen-specific adaptive immunity to SARS-CoV-2 in acute COVID-19 and associations with age and disease severity. Moderbacher et al.
Carolyn Rydyznski Moderbacher,Sydney I. Ramirez,Jennifer M. Dan,Alba Grifoni,Kathryn M. Hastie,Daniela Weiskopf,Simon Bélanger,Robert K. Abbott,Christina K. Kim,Jinyong Choi,Yu Kato,Eleanor G. Crotty,Cheryl Kim,Stephen A. Rawlings,Jose Mateus,Longping V. Tse,April Frazier,Ralph S. Baric,Bjoern Peters,Jason A. Greenbaum,Erica Ollmann Saphire,Davey M. Smith,Alessandro Sette,Shane Crotty +23 more
Journal ArticleDOI
Bcl-6 is the nexus transcription factor of T follicular helper cells via repressor-of-repressor circuits.
Jinyong Choi,Huitian Diao,Caterina E. Faliti,Jacquelyn Truong,Meghan Rossi,Simon Bélanger,Bingfei Yu,Ananda W. Goldrath,Matthew E. Pipkin,Shane Crotty,Shane Crotty +10 more
TL;DR: A comprehensive transcriptional map is provided depicting the regulatory circuitry controlled by Bcl-6 in determining T FH cell fate and function, via multiple repressor-of-repressor gene circuits.
Journal ArticleDOI
Bcl6-Mediated Transcriptional Regulation of Follicular Helper T cells (TFH)
TL;DR: In this paper, the authors focus on advances in understanding of Bcl6-mediated gene regulation of TFH functions, and the modulation of the TFH by other TFs.
Journal ArticleDOI
Ezh2 programs T FH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf
Fengyin Li,Fengyin Li,Zhouhao Zeng,Shaojun Xing,Shaojun Xing,Jodi A. Gullicksrud,Jodi A. Gullicksrud,Qiang Shan,Jinyong Choi,Vladimir P. Badovinac,Shane Crotty,Weiqun Peng,Hai-Hui Xue +12 more
TL;DR: Ezh2 orchestrates TFH-lineage specification and function maturation by integrating phosphorylation-dependent transcriptional activation and HMT-dependent gene repression, and promotes T follicular helper differentiation and helper activity.