Jiri Fajkus

TL;DR: Analysis of terminal restriction fragments in different tissues and ontogenetic stages showed that telomere lengths are stabilized precisely and do not change during plant growth and development, suggesting their precise control during plant ontogenesis; however, the telomeres length regulation mechanism could be unbalanced during in vitro dedifferentiation.

TL;DR: Using slot-blot and fluorescent in situ hybridization (FISH), polymerase chain reaction experiments indicated that there are short lengths of the sequence TTTAGGG dispersed in the genome but that these sequences are almost certainly too short to act as functional telomeres even if they were at the chromosome termini.

TL;DR: Investigating the architecture of telomeres in the dicot plants Silene latifolia and Arabidopsis thaliana using the PENT assay suggests that incomplete DNA replication of the lagging strand, rather than synthesis by telomerase is the primary mechanism for G-overhang synthesis in plants.

TL;DR: The data indicate that the A/T rich minisatellite might have evolved in response to the loss of Arabidopsis-type telomeres, and might indicate past recombination and chromosomal fusion events, processes that may have contributed to the large size of Cestrum chromosomes.

TL;DR: It is shown that patients suffering from chronic myeloid leukaemia express high levels of FGFR3 mRNA in white blood cells (WBCs), and the changing levels ofFGFR3 transcripts in WBCs may have prognostic significance in CML.