J
Jiro Yoshida
Researcher at Hiroshima University
Publications - 20
Citations - 606
Jiro Yoshida is an academic researcher from Hiroshima University. The author has contributed to research in topics: Allixin & Alkyl. The author has an hindex of 12, co-authored 20 publications receiving 563 citations. Previous affiliations of Jiro Yoshida include Kyoto Pharmaceutical University.
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Journal ArticleDOI
Determination of Seven Organosulfur Compounds in Garlic by High-Performance Liquid Chromatography
TL;DR: A newly developed analytical method with a rapid and simple sample preparation to determine four sulfoxides and three gamma-glutamyl peptides in garlic is reported, which offers some advantages over the currently accepted techniques including specificity, speed, and ease of use.
Journal ArticleDOI
Oral administration of a zinc complex improves type 2 diabetes and metabolic syndromes.
Yusuke Adachi,Jiro Yoshida,Yukihiro Kodera,Tamás Kiss,Tamás Jakusch,Éva A. Enyedy,Yutaka Yoshikawa,Hiromu Sakurai +7 more
TL;DR: Daily oral administrations of Zn(tanm)(2) for 4 weeks in KKA(y) mice significantly improved hyperglycemia, glucose intolerance, insulin resistance, hyperleptinemia, obesity, and hypertension and increased depressed plasma adiponectin levels in the mice.
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Bis(allixinato)oxovanadium(IV) complex is a potent antidiabetic agent: studies on structure-activity relationship for a series of hydroxypyrone-vanadium complexes.
TL;DR: Complex 3 with a high in vitro insulin-mimetic activity in terms of both free fatty acid-release inhibitory and glucose-uptake enhancing activities in isolated rat adipocytes exhibited a high hypoglycemic effect in type 1 diabetic model mice by both intraperitoneal injections and oral administrations, and is proposed to be one of the most effective candidates for antidiabetic therapy.
Journal ArticleDOI
A new insulin-mimetic bis(allixinato)zinc(II) complex: structure–activity relationship of zinc(II) complexes
Yusuke Adachi,Jiro Yoshida,Yukihiro Kodera,Akira Kato,Yutaka Yoshikawa,Yoshitane Kojima,Hiromu Sakurai +6 more
TL;DR: It is concluded that the Zn(alx)2 complex is a novel potent candidate for the treatment of type 2 diabetes mellitus and possesses greater in vivo anti-diabetic activity than Zn (ma)2.
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Tetrahydro-β-Carboline Derivatives in Aged Garlic Extract Show Antioxidant Properties
TL;DR: The data suggest that THbetaCs, which are formed during the natural aging process, are potent antioxidants in aged garlic extract and thus may be useful for the prevention of diseases associated with oxidative damage.