Joachim Saloga

TL;DR: Results show that melanoma‐derived factors convert DC‐antigen presenting cell function to tolerance induction against tumor tissue, changing tumor DCs to “silencers” of anti‐tumoral immune responses.

TL;DR: Meta-analyses provide unequivocal evidence of the efficacy of SCIT and SLIT for certain allergen sources and age groups and require product-specific evaluation.

TL;DR: The data indicate that in insect venom allergic subjects, VIT not only induces a rapid shift in cytokine expression from Th2 to Th1 cytokines, but also leads to induction of the immunosuppressive cytokine IL‐10, which may be important for the limitation of potentially harmful allergen‐specific Th1 responses.

TL;DR: The data indicate that murine KC are a source of both IL-18 mRNA and functional protein, identifying KC as a major source of IL-20 and IFN-gamma.

TL;DR: In an attempt to show the induction of antigen-specific tolerance in these mice in vitro, regional lymph nodes of mice initially treated with TNCB plus IL-10 and control-treated mice (groups 2 and 3) were prepared and cultured in the presence of TNBS, dinitrobenzene sulfonate (DNBS), or medium to measure antigen- specific proliferation.