J
Joan Levine
Researcher at University of Southern California
Publications - 1
Citations - 1811
Joan Levine is an academic researcher from University of Southern California. The author has contributed to research in topics: MLH1 & CpG site. The author has an hindex of 1, co-authored 1 publications receiving 1704 citations.
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CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer.
Daniel J. Weisenberger,Kimberly D. Siegmund,Mihaela Campan,Joanne P. Young,Tiffany I. Long,Mark A Faasse,Gyeong Hoon Kang,Martin Widschwendter,Deborah Weener,Daniel D. Buchanan,Hoey Koh,Lisa A. Simms,Melissa A. Barker,Barbara A. Leggett,Joan Levine,Myungjin Kim,Amy J. French,Stephen N. Thibodeau,Jeremy R. Jass,Robert W. Haile,Peter W. Laird +20 more
TL;DR: A systematic, stepwise screen of 195 CpG island methylation markers using MethyLight technology found that CIMP-positive (CIMP+) tumors convincingly represent a distinct subset, encompassing almost all cases of tumors with BRAFmutation (odds ratio = 203).