J
Joan Overhauser
Researcher at Thomas Jefferson University
Publications - 72
Citations - 2946
Joan Overhauser is an academic researcher from Thomas Jefferson University. The author has contributed to research in topics: Chromosome 18 & Gene. The author has an hindex of 32, co-authored 72 publications receiving 2881 citations. Previous affiliations of Joan Overhauser include University of California, Irvine.
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Journal ArticleDOI
Non-function of a Moloney murine leukaemia virus regulatory sequence in F9 embryonal carcinoma cells
TL;DR: Evidence is presented which supports the hypothesis that certain M-MuLV regulatory sequences do not function in EC cells and that viral gene expression is not observed even at early times.
Journal Article
Human Exonuclease I Interacts with the Mismatch Repair Protein hMSH2
Christoph Schmutte,Rodica Catrinel Marinescu,Margaret M. Sadoff,Shawn Guerrette,Joan Overhauser,Richard Fishel +5 more
TL;DR: In this paper, a human exonuclease (hExoI) was found to interact strongly with the human MMR protein hMSH2, suggesting its involvement in the MMR process and/or DNA recombination.
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Hemizygosity of δ-Catenin (CTNND2) Is Associated with Severe Mental Retardation in Cri-du-Chat Syndrome
TL;DR: Findings and the properties of δ-catenin as a neuronal-specific protein, expressed early in development and involved in cell motility, support its role in the mental retardation of CDCS when present in only one copy.
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Transformation properties of type 5 adenovirus mutants that differentially express the E1A gene products
TL;DR: Type 5 adenovirus mutants that differentially express E1A 13S, 12S, or 9S mRNAs were constructed to study the role of their gene products in transformation and the plasmid pD1/D2, which directs the synthesis of the 54-AA protein only, was found to transform baby rat kidney cells at low frequency.
Journal ArticleDOI
Molecular and phenotypic mapping of the short arm of chromosome 5: sublocalization of the critical region for the cri-du-chat syndrome
Joan Overhauser,Xlaogu Huang,Meryl Gersh,Wesley Wilson,Jeanette McMahon,Ulla Bengtsson,Katherine Rojas,Marvin Meyer,John J. Wasmuth +8 more
TL;DR: The results demonstrate the need for careful characterization of a 5p deletion in prenatal cases before clinical predictions are made and identify several chromosomal regions that were involved in specific clinical features.