J
JoAnn Suzich
Researcher at MedImmune
Publications - 65
Citations - 5440
JoAnn Suzich is an academic researcher from MedImmune. The author has contributed to research in topics: Virus & Epitope. The author has an hindex of 38, co-authored 65 publications receiving 4968 citations. Previous affiliations of JoAnn Suzich include University of Rochester.
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Journal ArticleDOI
Systemic immunization with papillomavirus L1 protein completely prevents the development of viral mucosal papillomas
JoAnn Suzich,Shin-je Ghim,Frances J. Palmer-Hill,Wendy I. White,J. K. Tamura,J. A. Bell,J. A. Newsome,A. B. Jenson,Richard Schlegel +8 more
TL;DR: The results indicate the feasibility of developing a human vaccine to prevent mucosal papillomas, which can progress to malignancy, and suggest adjuvants appeared useful for prolonging the host immune response.
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Enhanced humoral and memory B cellular immunity using HPV16/18 L1 VLP vaccine formulated with the MPL/aluminium salt combination (AS04) compared to aluminium salt only
Sandra L. Giannini,Emmanuel Hanon,Philippe Moris,Marcelle Van Mechelen,Sandra Morel,Francis Dessy,Marc Fourneau,Brigitte Desiree Alberte Colau,JoAnn Suzich,Genevieve Losonksy,Marie-Therese Martin,Gary Dubin,Martine Wettendorff +12 more
TL;DR: The role of the AS04 adjuvant, which includes the immunostimulant MPL, in triggering a persistent vaccine-induced immune response of high quality is strongly supported.
Journal ArticleDOI
Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes.
JoAnn Suzich,J K Tamura,Frances J. Palmer-Hill,Paul Warrener,A Grakoui,C M Rice,S M Feinstone,Marc S. Collett +7 more
TL;DR: It is experimentally demonstrated that the NS3 protein from a member of the third genus of Flaviviridae, human hepatitis C virus (HCV), also possesses a polynucleotide-stimulated NTPase activity.
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Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes
Nicole L. Kallewaard,Davide Corti,Patrick J. Collins,Ursula Neu,Josephine M. McAuliffe,Ebony Benjamin,Leslie Wachter-Rosati,Frances J. Palmer-Hill,Andy Q. Yuan,Philip A. Walker,Matthias K. Vorlaender,Siro Bianchi,Barbara Guarino,Anna De Marco,Fabrizia Vanzetta,Gloria Agatic,Mathilde Foglierini,Debora Pinna,Blanca Fernandez-Rodriguez,Alexander Fruehwirth,Chiara Silacci,Roksana W. Ogrodowicz,Stephen R. Martin,Federica Sallusto,JoAnn Suzich,Antonio Lanzavecchia,Antonio Lanzavecchia,Qing Zhu,Steven J. Gamblin,John J. Skehel +29 more
TL;DR: The unprecedented breadth and potency of neutralization by MEDI8852 support its development as immunotherapy for influenza virus-infected humans.
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A multifunctional bispecific antibody protects against Pseudomonas aeruginosa
Antonio DiGiandomenico,Ashley E. Keller,Cuihua Gao,Godfrey Rainey,Paul Warrener,Mareia M. Camara,Jessica Bonnell,Ryan Fleming,Binyam Bezabeh,Nazzareno Dimasi,Bret R. Sellman,Jamese J. Hilliard,Caitlin M. Guenther,Vivekananda Datta,Wei Zhao,Changshou Gao,Xiang-Qing Yu,JoAnn Suzich,C. Kendall Stover +18 more
TL;DR: Two antibody studies suggest that multifunctional bispecific antibody approaches may be a promising platform for targeting other antibiotic-resistant bacterial pathogens.