Joanna M. Dragich

TL;DR: Evidence is provided that hippocampal cells contain an autonomous circadian clock and that the clock gene Per2 may play a role in the regulation of long-term potentiation and in the recall of some forms of learned behaviour.

TL;DR: Although much is known about the biochemical function of MeCP2, the phenotype of Rett syndrome suggests that it plays an unexplored but critical role in development and maintenance of the nervous system.

TL;DR: The differential distribution of the Mecp2e1 and MecP2e2 transcripts indicates regional and developmental regulation of Mec p2 splicing in the postnatal mouse brain.

TL;DR: It is reported that the Autophagy linked FYVE protein, previously identified as a molecular scaffold between the ubiquitinated cargo and the autophagic machinery, is required for the formation of axonal tracts throughout the brain and spinal cord, including theformation of the major forebrain commissures.

TL;DR: It is concluded that the anatomical expression, biophysical properties, and pharmacological profiles measured are all consistent with the SCN IA current being generated by Kv4 channels, and suggest a role for IA in the regulation of spontaneous action potential firing during the transitions between day/night and in the integration of synaptic inputs to SCN neurons throughout the daily cycle.