J
Joanna Rejman
Researcher at Ghent University
Publications - 15
Citations - 4192
Joanna Rejman is an academic researcher from Ghent University. The author has contributed to research in topics: Transfection & Internalization. The author has an hindex of 10, co-authored 15 publications receiving 3873 citations. Previous affiliations of Joanna Rejman include Free University of Berlin & Vita-Salute San Raffaele University.
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Journal ArticleDOI
Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis
TL;DR: The data indicate that the size itself of (ligand-devoid) particles can determine the pathway of entry in non-phagocytic B16 cells, and kinetic parameters may determine the almost exclusive internalization of such particles along this pathway rather than via caveolae.
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Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes
TL;DR: Fluorescence colocalization studies with a lysosomal marker, AlexaFluor-dextran, revealed that polyplexes taken up by clathrin-mediated endocytosis are targeted to the lysOSomal compartment for degradation, while the polyplexed via caveolae escape this compartment, permitting efficient transfection.
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Pseudomonas aeruginosa microevolution during cystic fibrosis lung infection establishes clones with adapted virulence.
Alessandra Bragonzi,Moira Paroni,Alessandro Nonis,Nina Cramer,S. Montanari,Joanna Rejman,Clelia Di Serio,Gerd Döring,Burkhard Tümmler +8 more
TL;DR: Findings indicate that clonal expansion of P. aeruginosa strains during microevolution within CF lungs leads to populations with altered but not reduced virulence, which may serve to define virulence determinants as targets for novel therapies.
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Gene Transfer by Means of Lipo- and Polyplexes: Role of Clathrin and Caveolae-Mediated Endocytosis
TL;DR: The data suggest that improvement of non-viral gene transfection could very much benefit from controlling particle size, which would allow targeting of particle internalization via a non-degradative pathway, involving caveolae-mediated endocytosis.
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Stimuli-responsive electrospun fibers and their applications
Chaobo Huang,Stefaan J. Soenen,Joanna Rejman,Bart Lucas,Kevin Braeckmans,Jo Demeester,Stefaan C. De Smedt +6 more
TL;DR: An overview of recent advances made in the development and application of stimuli-responsive electrospun fibers is given and several novel biomedical applications are discussed.