J
Johan Lindholm
Researcher at Karolinska University Hospital
Publications - 59
Citations - 3928
Johan Lindholm is an academic researcher from Karolinska University Hospital. The author has contributed to research in topics: Cancer & Epidermoid carcinoma. The author has an hindex of 25, co-authored 59 publications receiving 3767 citations. Previous affiliations of Johan Lindholm include Karolinska Institutet.
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Incidence of human papillomavirus (HPV) positive tonsillar carcinoma in Stockholm, Sweden: an epidemic of viral-induced carcinoma?
Anders Näsman,Per Attner,Lalle Hammarstedt,Juan Du,Mathilda Eriksson,Géraldine Giraud,Sofie Ährlund-Richter,Linda Marklund,Mircea Romanitan,David Lindquist,Torbjörn Ramqvist,Johan Lindholm,Pär Sparén,Weimin Ye,Hanna Dahlstrand,Eva Munck-Wikland,Tina Dalianis,Tina Dalianis +17 more
TL;DR: The incidence of HPV‐positive cancers is still increasing in the County of Stockholm, suggesting an epidemic of a virus‐induced carcinoma, with soon practically all tonsillar SCC being HPV positive, as in cervical cancer.
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Human papillomavirus as a risk factor for the increase in incidence of tonsillar cancer
Lalle Hammarstedt,David Lindquist,Hanna Dahlstrand,Mircea Romanitan,Liselotte Onelöv,Jeanna Joneberg,Nomi Creson,Johan Lindholm,Weimin Ye,Tina Dalianis,Eva Munck-Wikland +10 more
TL;DR: A highly significant and parallel increase both in the incidence of tonsillar cancer and the proportion of HPV‐positive tumors is demonstrated, which should definitely influence future preventive strategies as well as treatment for this type of cancer.
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Evidence of the Oncologic Superiority of Cylindrical Abdominoperineal Excision for Low Rectal Cancer
TL;DR: Cylindrical APE performed in the prone position for low rectal cancer removes more tissue around the tumor that leads to a reduction in CRM involvement and intraoperative perforations, which should reduce local disease recurrence.
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Human papillomavirus type 16 is episomal and a high viral load may be correlated to better prognosis in tonsillar cancer
Hanna Mellin,Liselotte Dahlgren,Eva Munck-Wikland,Johan Lindholm,Hodjattallah Rabbani,Mina Kalantari,Tina Dalianis +6 more
TL;DR: HPV‐16 is mainly episomal in tonsillar cancer, the viral load showed a wide distribution and the clinical outcome in this study was better when the HPV load was higher.
Journal ArticleDOI
The role of human papillomavirus in the increased incidence of base of tongue cancer
Per Attner,Juan Du,Anders Näsman,Lalle Hammarstedt,Torbjörn Ramqvist,Johan Lindholm,Linda Marklund,Tina Dalianis,Tina Dalianis,Eva Munck-Wikland +9 more
TL;DR: The incidence of base of tongue cancer, as well as the proportion of HPV‐positive tumors, has increased in Sweden during the study period, suggesting that HPV may contribute to this increase.