J
Johan Lindholm
Researcher at Karolinska University Hospital
Publications - 59
Citations - 3928
Johan Lindholm is an academic researcher from Karolinska University Hospital. The author has contributed to research in topics: Cancer & Epidermoid carcinoma. The author has an hindex of 25, co-authored 59 publications receiving 3767 citations. Previous affiliations of Johan Lindholm include Karolinska Institutet.
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Journal ArticleDOI
Human papillomavirus is a favourable prognostic factor in tonsillar cancer and its oncogenic role is supported by the expression of E6 and E7
David Lindquist,Mircea Romanitan,Lalle Hammarstedt,Anders Näsman,Hanna Dahlstrand,Johan Lindholm,Liselotte Onelöv,Torbjörn Ramqvist,Weimin Ye,Eva Munck-Wikland,Tina Dalianis +10 more
TL;DR: The presence of HPV‐16, but not viral load, in tonsillar cancer was shown to be a favourable prognostic factor for clinical outcome, and E6 and/or E7 were expressed in almost all assessable HPV‐ 16 positive cases, supporting an oncogenic role of HPV•16 in tonsilar cancer.
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Psoriasis patients with diabetes type 2 are at high risk of developing liver fibrosis during methotrexate treatment
Peter Rosenberg,Hanna Urwitz,Anders Johannesson,Anne-Marie Ros,Johan Lindholm,Nils Kinnman,Rolf Hultcrantz +6 more
TL;DR: Patients with methotrexate treated psoriasis and risk factors for liver disease, especially diabetes type 2 or overweight, are at higher risk of developing severe liver fibrosis compared to those without such risk factors, even when lower cumulative metotrexate doses are given.
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Human papillomavirus is more common in base of tongue than in mobile tongue cancer and is a favorable prognostic factor in base of tongue cancer patients.
Liselotte Dahlgren,Hanna Dahlstrand,David Lindquist,Anders Högmo,Linda Björnestål,Johan Lindholm,Bertil Lundberg,Tina Dalianis,Eva Munck-Wikland +8 more
TL;DR: HPV is significantly more common in base of tongues cancer than in mobile tongue cancer, and has a positive impact on disease‐specific survival in patients with base of tongue cancer.
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Low risk of recurrence of enchondroma and low-grade chondrosarcoma in extremities:80 patients followed for 2-25 years
TL;DR: The results imply that enchondroma and low-grade chondrosarcoma of the extremities should be treated with limited surgery, and the morbidity associated with en bloc resection and reconstruction can apparently be obviated without jeopardizing the limb or survival.
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Comparative genomic hybridization analysis of tonsillar cancer reveals a different pattern of genomic imbalances in human papillomavirus-positive and -negative tumors.
Liselotte Dahlgren,Hanna Mellin,Danny Wangsa,Kerstin Heselmeyer-Haddad,Linda Björnestål,Johan Lindholm,Eva Munck-Wikland,Gert Auer,Thomas Ried,Tina Dalianis +9 more
TL;DR: As expected, patients with an HPV‐positive tumor had a statistically significantly better disease‐specific survival than patients with a HPV‐negative tumor, and the most common changes, e.g., gain on 3q or 8q, loss on 11q or 13 and loss on chromosome 7q in HPV‐ negative tumors, did not have any influence on prognosis.