J
Johannes C. Klein
Researcher at University of Oxford
Publications - 95
Citations - 6330
Johannes C. Klein is an academic researcher from University of Oxford. The author has contributed to research in topics: Parkinson's disease & Magnetic resonance imaging. The author has an hindex of 32, co-authored 88 publications receiving 5579 citations. Previous affiliations of Johannes C. Klein include Centre Hospitalier de Luxembourg & John Radcliffe Hospital.
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Journal ArticleDOI
Acquisition and voxelwise analysis of multi-subject diffusion data with Tract-Based Spatial Statistics
Stephen M. Smith,Heidi Johansen-Berg,Mark Jenkinson,Daniel Rueckert,Thomas E. Nichols,Thomas E. Nichols,Karla L. Miller,Matthew D. Robson,Derek K. Jones,Johannes C. Klein,Andreas J. Bartsch,Timothy E.J. Behrens +11 more
TL;DR: This protocol describes the MRI data acquisition and analysis protocols required for TBSS studies of localized change in brain connectivity across multiple subjects, and aims to solve crucial issues of cross-subject data alignment, allowing localized cross- subject statistical analysis.
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The nucleus accumbens: a target for deep brain stimulation in obsessive-compulsive- and anxiety-disorders.
Volker Sturm,Doris Lenartz,Athanasios Koulousakis,Harald Treuer,Karl Herholz,Johannes C. Klein,Joachim Klosterkötter +6 more
TL;DR: The shell region of the right nucleus accumbens is chosen as target for deep brain stimulation (DBS) in a pilot-series of four patients with severe obsessive-compulsive- and anxiety-disorders, with significant reduction in severity of symptoms.
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Human Motor Corpus Callosum: Topography, Somatotopy, and Link between Microstructure and Function
Mathias Wahl,Birgit Lauterbach-Soon,Elke Hattingen,Patrick Jung,Oliver C. Singer,Steffen Volz,Johannes C. Klein,Helmuth Steinmetz,Ulf Ziemann +8 more
TL;DR: It is demonstrated that CMFs connecting defined body representations of M1 map onto a circumscribed region in the CC in a somatotopically organized manner, and the significant and topographically specific positive correlation between FA and interhemispheric inhibition strongly suggests that microstructure can be directly linked to functional connectivity.
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Dementia in Parkinson disease Functional imaging of cholinergic and dopaminergic pathways
Rüdiger Hilker,Anne V. Thomas,Johannes C. Klein,Simon Weisenbach,Elke Kalbe,Lothar Burghaus,Andreas H. Jacobs,Karl Herholz,Wolf-Dieter Heiss +8 more
TL;DR: The finding of a closely associated striatal FDOPA and cortical MP4A binding reduction suggests a common disease process leading to a complex transmitter deficiency syndrome in PDD.
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Diffusion-weighted imaging tractography-based parcellation of the human lateral premotor cortex identifies dorsal and ventral subregions with anatomical and functional specializations.
Valentina Tomassini,Saad Jbabdi,Johannes C. Klein,Timothy E.J. Behrens,Carlo Pozzilli,Paul M. Matthews,Matthew F. S. Rushworth,Heidi Johansen-Berg +7 more
TL;DR: In this article, diffusion tractography was used to identify a reproducible border between dorsal and ventral subregions of human precentral gyrus, which corresponded closely to the location of a functional border defined using previous functional magnetic resonance imaging studies.