Joachim Klosterkötter

TL;DR: The relatively new field of HR research in psychosis has the potential to shed light on the development of major psychotic disorders and to alter their course and provides a rationale for service provision to those in need of help who could not previously access it.

TL;DR: The Bonn Scale for the Assessment of Basic Symptoms operationalization of prodromal symptoms performed well in the early detection of schizophrenia and might be useful for the prediction of the disorder, especially if it is further refined to select those items with particularly high prognostic accuracy.

TL;DR: It is suggested that inhibition of anandamide deactivation may contribute to the antipsychotic effects of cannabidiol potentially representing a completely new mechanism in the treatment of schizophrenia.

TL;DR: A differential predictive clinical model of transition to first-episode psychosis is developed that identified an increased risk of psychosis with appropriate prognostic accuracy in a sample of help-seeking patients.

TL;DR: The shell region of the right nucleus accumbens is chosen as target for deep brain stimulation (DBS) in a pilot-series of four patients with severe obsessive-compulsive- and anxiety-disorders, with significant reduction in severity of symptoms.