Volker Sturm

TL;DR: Preliminary findings suggest that DBS to the nucleus accumbens might be a hypothesis-guided approach for refractory major depression.

TL;DR: In this article, the authors demonstrate antidepressant and antianhedonic effects of DBS to the nucleus accumbens (NAcc) in patients suffering from very resistant forms of depression (treatment-resistant depression [TRD]), not responding to pharmacotherapy, psychotherapy, or electroconvulsive therapy (ECT).

TL;DR: DBS of the STN is safe with respect to neuropsychological and psychiatric effects in carefully selected patients during a 6-month follow-up period, although there is a selective decrease in frontal cognitive functions and an improvement in anxiety in patients after the treatment.

TL;DR: The shell region of the right nucleus accumbens is chosen as target for deep brain stimulation (DBS) in a pilot-series of four patients with severe obsessive-compulsive- and anxiety-disorders, with significant reduction in severity of symptoms.

TL;DR: The authors retrospectively compared 1-year results of bilateral deep brain stimulation of the subthalamic nucleus and internal pallidum in advanced PD and found about equal improvements in “off” period motor symptoms, dyskinesias, and fluctuations.