A lack of essential fatty acids as a possible cause of hyperactivity in children.

This comprehensive review contains a section on prostaglandins commenting on several possible interactions of prostaglandins on essential fatty acids (EFA). The section of prostaglandins reviews about 30 documents on sites of synthesis conversion of EFAs to prostaglandins and the physiological roles attributed to these compounds. Reported is a new approach to studies of the mechanism of action of EFAs which has been provided by the demonstration that ERAs can act as precursors of the physiologically active substances called prostaglandins. Prostaglandins function in many metabolic processes and seem to be involved in the control of blood pressure muscle contraction and enzyme and/or hormone induction.

Essential fatty acids reinvestigated.

Correction of essential fatty-acid deficiency in man by the cutaneous application of sunflower-seed oil.

Advances in investigative techniques have led to increasing reports of Crohn's disease in CF patients A retrospective review of the literature on IBD in CF showed findings characterized by ileocolitis with fistula formation; 83% required surgery A prospective survey of 11,321 CF patients attending 49 CF centers revealed 28 with IBD (25 Crohn's, three ulcerative colitis), ages 4-20 years, mean 156 years The prevalence rate of IBD (247/10(5)) was 7x controls and was accounted for by Crohn's disease (221/10(5)) which was 17x controls The mechanisms that predispose CF patients to Crohn's disease are discussed

Crohn's disease and cystic fibrosis

https://escholarship.org/content/qt8bj647t6/qt8bj647t6.pdf?t=oel4a4

John A. Balint

Papers

Fat absorption in essential fatty acid deficiency: a model experimental approach to studies of the mechanism of fat malabsorption of unknown etiology