Fat absorption in essential fatty acid deficiency: a model experimental approach to studies of the mechanism of fat malabsorption of unknown etiology
Susanne Bennett Clark,Susanne Bennett Clark,Susanne Bennett Clark,Thomas E. Ekkers,Thomas E. Ekkers,Thomas E. Ekkers,Akbal Singh,Akbal Singh,Akbal Singh,John A. Balint,John A. Balint,John A. Balint,Peter R. Holt,Peter R. Holt,Peter R. Holt,John B. Rodgers,John B. Rodgers,John B. Rodgers +17 more
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TLDR
Analysis of regions of intestine showed that this delay in transport was most marked in the midportion of the small intestine, and essential fatty acid deficiency appears to affect the synthesis or release of chylomicron lipid from the intestine.About:
This article is published in Journal of Lipid Research.The article was published on 1973-09-01 and is currently open access. It has received 46 citations till now. The article focuses on the topics: Triolein & Essential fatty acid.read more
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Journal ArticleDOI
A lack of essential fatty acids as a possible cause of hyperactivity in children.
Irene D. Colquhoun,Sally Bunday +1 more
TL;DR: The Hyperactive Children's Support Group (HCSG) in an organisation with over 70 branches in Britain devoted to helping such children and their families has come to the conclusion that many of these children have a deficiency of essential fatty acids (EFAs) either because they cannot metabolise linoleic acid normally, orBecause they cannot absorb EFAs normally from the gut, or because their EFA requirements are higher than normal.
Journal Article
Essential fatty acids reinvestigated.
R B Alfin-Slater,Aftergood L +1 more
TL;DR: A comprehensive review of prostaglandins on essential fatty acids (EFA) is presented in this article, with a focus on several possible interactions of prostags on EFA.
Journal ArticleDOI
Correction of essential fatty-acid deficiency in man by the cutaneous application of sunflower-seed oil.
TL;DR: The results suggest that even if percutaneous absorption of the oil is complete, the daily requirement for linoleic acid in adult man may be only 2-3 mg.
Journal ArticleDOI
Crohn's disease and cystic fibrosis
TL;DR: A retrospective review of the literature on IBD in CF showed findings characterized by ileocolitis with fistula formation; 83% required surgery, and the mechanisms that predispose CF patients to Crohn's disease are discussed.
Journal ArticleDOI
Intestinal Phospholipid Remodeling Is Required for Dietary-Lipid Uptake and Survival on a High-Fat Diet
Bo Wang,Xin Rong,Mark A. Duerr,Daniel J. Hermanson,Per Niklas Hedde,Jinny S. Wong,Thomas Q. de Aguiar Vallim,Benjamin F. Cravatt,Enrico Gratton,David A. Ford,Peter Tontonoz +10 more
TL;DR: It is demonstrated that the LXR-responsive phospholipid-remodeling enzyme Lpcat3 modulates intestinal fatty acid and cholesterol absorption and is required for survival on a high-fat diet, and that loss of LpCat3 amplifies the production of gut hormones, including GLP-1 and oleoylethanolamide, in response to high- fat feeding.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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Lipid composition and permeability of liposomes.
TL;DR: Comparisons of the permeability of the liposomes of phospholipids with asymmetric chains are much more permeable than those of lecithins with chains of equal length but with the same total number of paraffin carbon atoms suggests that, certainly at lower temperatures, the model structures are muchMore permeable.
Journal ArticleDOI
The effect of dietary fat on the molecular species of lecithin from rat liver.
TL;DR: Differences in diet induced significant variations in the proportions of the various lecithin species and also brought about qualitative differences, which may contribute to preserving the liquid-crystalline nature of these lipids in membrane structures.
Journal ArticleDOI
Essential fatty acids reinvestigated.
R B Alfin-Slater,Aftergood L +1 more
TL;DR: There is a new approach to studies of the mechanism of action of EFAs which has been provided by the demonstration that ERAs can act as precursors of the physiologically active substances called prostaglandins.
Journal Article
Essential fatty acids reinvestigated.
R B Alfin-Slater,Aftergood L +1 more
TL;DR: A comprehensive review of prostaglandins on essential fatty acids (EFA) is presented in this article, with a focus on several possible interactions of prostags on EFA.